Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PDLIM1 and ACTN2
Number of citations of the paper that reports this interaction (PMID
10861853
)
9
Data Source:
HPRD
(two hybrid, in vivo)
PDLIM1
ACTN2
Gene Name
PDZ and LIM domain 1
actinin, alpha 2
Image
Gene Ontology Annotations
Cellular Component
Transcription Factor Complex
Cytoplasm
Cytoskeleton
Focal Adhesion
Extracellular Region
Cytosol
Cytoskeleton
Actin Filament
Focal Adhesion
Z Disc
Filopodium
Cortical Actin Cytoskeleton
Platelet Alpha Granule Lumen
Pseudopodium
Dendritic Spine
Extracellular Vesicular Exosome
Molecular Function
Transcription Coactivator Activity
Zinc Ion Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Cytoskeletal Protein Binding
Structural Constituent Of Muscle
LIM Domain Binding
Thyroid Hormone Receptor Coactivator Activity
Titin Binding
Identical Protein Binding
Ion Channel Binding
Protein Dimerization Activity
Actin Filament Binding
FATZ Binding
Titin Z Domain Binding
Biological Process
Response To Hypoxia
Regulation Of Transcription, DNA-templated
Response To Oxidative Stress
Platelet Degranulation
Cell Adhesion
Synaptic Transmission
Blood Coagulation
Microspike Assembly
Muscle Filament Sliding
Platelet Activation
Regulation Of Membrane Potential
Regulation Of Apoptotic Process
Negative Regulation Of Potassium Ion Transport
Positive Regulation Of Potassium Ion Transport
Focal Adhesion Assembly
Protein Homotetramerization
Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Protein Localization To Cell Surface
Positive Regulation Of Receptor Activity
Pathways
Striated Muscle Contraction
Platelet degranulation
CREB phosphorylation through the activation of Ras
Activation of NMDA receptor upon glutamate binding and postsynaptic events
Response to elevated platelet cytosolic Ca2+
CREB phosphorylation through the activation of CaMKII
Nephrin interactions
Platelet activation, signaling and aggregation
Unblocking of NMDA receptor, glutamate binding and activation
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ras activation uopn Ca2+ infux through NMDA receptor
Transmission across Chemical Synapses
Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
ACTN1
ACTN2
ACTN4
AGK
GFAP
MAPK6
PGS1
PITX2
RLIM
RPS6KA5
STK35
SUPT4H1
VIM
59 interactors:
ACTN3
ADAM12
ADORA2A
ANG
ATXN2
ATXN7
BRMS1L
CAMK2A
CAMK2D
CAMK2G
CAPN1
COIL
DISC1
DLG1
DLG4
EPS8L1
ERBB2IP
FAM154A
FBXL22
GRIN1
GRIN2B
ITGB3BP
KAT2B
KCNA4
KCNA5
KCNN2
LDB3
LRP12
LRRC7
MED14
MICALL2
MOS
MYOZ1
MYOZ2
MYOZ3
MYPN
NCOA2
NCOR1
NOS3
NR1I2
NRIP1
PALLD
PDLIM1
PDLIM3
PKD2
RAVER1
RPL35
RTP5
SELE
SNAI1
SNW1
SP100
SSX2IP
ST7
SYNPO2
TNN
TTN
UTRN
ZNF446
Entrez ID
9124
88
HPRD ID
09326
00019
Ensembl ID
ENSG00000107438
ENSG00000077522
Uniprot IDs
O00151
B2RCS5
P35609
Q59FD9
PDB IDs
1X62
2PKT
1H8B
1HCI
1QUU
Enriched GO Terms of Interacting Partners
?
Protein Localization To Tight Junction
Bergmann Glial Cell Differentiation
Protein Localization To Cell Junction
Platelet Degranulation
Intermediate Filament Organization
Actin Crosslink Formation
Astrocyte Development
Actin-myosin Filament Sliding
Focal Adhesion Assembly
Muscle Filament Sliding
Platelet Activation
Cell Junction Assembly
Cell-cell Junction Organization
Intermediate Filament Cytoskeleton Organization
Astrocyte Differentiation
Intermediate Filament-based Process
Actin-mediated Cell Contraction
Tight Junction Assembly
Adherens Junction Assembly
Actin Filament-based Process
Positive Regulation Of Ion Transmembrane Transporter Activity
Cell-substrate Junction Assembly
Response To Wounding
Positive Regulation Of Transporter Activity
Actin Filament Bundle Assembly
Actin Filament-based Movement
Histone H2A-S1 Phosphorylation
Subthalamic Nucleus Development
Prolactin Secreting Cell Differentiation
Random Inactivation Of X Chromosome
Positive Regulation Of Schwann Cell Proliferation
Superior Vena Cava Morphogenesis
Apical Junction Assembly
Exocytosis
Positive Regulation Of Ion Transmembrane Transport
Adherens Junction Organization
Cell Proliferation Involved In Outflow Tract Morphogenesis
Subthalamus Development
Left Lung Morphogenesis
Pulmonary Vein Morphogenesis
Blood Coagulation
Glial Cell Development
Hemostasis
Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis
Extraocular Skeletal Muscle Development
Pulmonary Myocardium Development
Positive Regulation Of Pinocytosis
Left Lung Development
Cell-cell Junction Assembly
Negative Regulation Of Neuron Projection Development
Cytoskeleton Organization
Regulation Of Ion Transport
Organelle Organization
Cell Communication
Actin Filament-based Process
Signaling
Cellular Component Assembly
Positive Regulation Of Cellular Metabolic Process
Regulation Of Ion Transmembrane Transport
Anatomical Structure Development
Synaptic Transmission
Positive Regulation Of Metabolic Process
Cell Development
Signal Transduction
Movement Of Cell Or Subcellular Component
Cell Differentiation
Cell-cell Signaling
Regulation Of Cellular Process
Rhythmic Process
Developmental Process
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Actin Cytoskeleton Organization
Anatomical Structure Morphogenesis
Protein Complex Assembly
Regulation Of Potassium Ion Transport
Striated Muscle Cell Differentiation
Regulation Of Signaling
Anatomical Structure Formation Involved In Morphogenesis
Response To Organic Substance
Regulation Of Sodium Ion Transport
Response To Abiotic Stimulus
Muscle System Process
Negative Regulation Of Transport
Striated Muscle Cell Development
Positive Regulation Of Cellular Biosynthetic Process
Myofibril Assembly
Establishment Or Maintenance Of Apical/basal Cell Polarity
Transcription Initiation From RNA Polymerase II Promoter
Cell Adhesion
Muscle Cell Development
Cellular Calcium Ion Homeostasis
Regulation Of Receptor Internalization
Regulation Of Cellular Response To Heat
Response To Stimulus
Regulation Of Histone Deacetylase Activity
Calcium Ion Homeostasis
Regulation Of Calcium Ion Transport
Locomotion
Negative Regulation Of Ion Transport
Tagcloud
?
actinin
barr
cd99
cdk8
dnajb2
e2f
e2f2
ebv
epstein
fatigue
hsp40
hybridized
indicative
infectious
infective
irritability
isg20
malaise
microarrays
mononucleosis
oligonucleotides
pbmc
persist
pilot
recovered
resolve
somnolence
spotted
uneventfully
Tagcloud (Difference)
?
actinin
barr
cd99
cdk8
dnajb2
e2f
e2f2
ebv
epstein
fatigue
hsp40
hybridized
indicative
infectious
infective
irritability
isg20
malaise
microarrays
mononucleosis
oligonucleotides
pbmc
persist
pilot
recovered
resolve
somnolence
spotted
uneventfully
Tagcloud (Intersection)
?