DAZAP2 and DAZL

Number of citations of the paper that reports this interaction (PMID 10857750)
34

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		DAZAP2	DAZL
Gene Name		DAZ associated protein 2	deleted in azoospermia-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Polysome
	Molecular Function	Protein Binding WW Domain Binding	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding
	Biological Process		Oocyte Maturation Female Meiosis II Multicellular Organismal Development Germ Cell Development Spermatogenesis Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		86 interactors: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FAM46B FAM46C FBN3 GPSM1 HGS HIP1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MED31 NDUFA5 NEDD4 NEDD4L NOC4L OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPT2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581	5 interactors: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2
Entrez ID		9802	1618
HPRD ID		08463	09029
Ensembl ID		ENSG00000183283	ENSG00000092345
Uniprot IDs		E9PB45 Q15038	Q92904
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Protein Processing Regulation Of ERBB Signaling Pathway Protein Ubiquitination Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Virion Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Signaling Intracellular Transport Of Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Metabolic Process RNA Biosynthetic Process Endosomal Transport Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type I Interferon Production Transforming Growth Factor Beta Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress	Spermatogenesis Male Gamete Generation Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Reproduction Single Organism Reproductive Process Reproductive Process Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Stress Granule Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Maternal Placenta Development Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translational Initiation Positive Regulation Of Translation Maternal Process Involved In Female Pregnancy Regulation Of MRNA Processing Regulation Of RNA Splicing
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Tagcloud (Difference) ?			122c 2012cb944901 9qh azoospermia blimp1 ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
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