DAZAP2 and UBXN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DAZAP2	UBXN7
Description		DAZ associated protein 2	UBX domain protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Protein-containing Complex	Nucleus Nucleoplasm Cytosol VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	P53 Binding Transcription Coactivator Activity Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding Protein Serine/threonine Kinase Binding DNA-binding Transcription Factor Binding	Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Protein Destabilization Stress Granule Assembly Positive Regulation Of DNA-templated Transcription	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation KEAP1-NFE2L2 pathway
Drugs
Diseases
GWAS			Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)
Interacting Genes		168 interacting genes: AATF ACOT7 AOC1 ARID5A ATXN1 ATXN1L BAG3 BATF2 BHLHE40 C1orf94 CALCOCO2 CAMK2A CAPN15 CCDC120 CDK4 CELF5 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 DESI1 DTX2 EPN1 EPN2 EPN3 ESRP1 EXD3 FAM168A FAM83A FBN3 FOXH1 GGA3 GPS2 GPSM1 HEY1 HGS HIP1 HIPK2 INCA1 KLHL42 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LGALS9 LITAF LMO2 MAGED1 MAPK1IP1L MED31 MINDY1 MINDY3 MTURN MYEOV MYOZ3 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTUB2 OTUD7B OTULIN PATZ1 PDIK1L PEF1 PITX2 PLEKHB2 PLEKHF2 PLSCR1 PLSCR4 POGZ POLI PROP1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 RABGEF1 RAD18 RAD23A RAMAC RBFOX1 RBFOX2 RBM11 RBM24 RBM43 RBPMS RHOXF2 RNF115 RNF208 RNF44 ROR2 RPS27A RUNX1 SEPTIN2 SIAH1 SMAP2 SMURF2 SNRPC SOX10 SOX6 SPMIP9 SQSTM1 STAM2 STAT6 TAX1BP1 TBX6 TCF7L2 TENT5B TENT5C TFG TIAL1 TLE1 TLE5 TNIP1 TNIP3 TOLLIP TOM1 TP53 UBA52 UBAC1 UBAP2 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE2E3 UBE2V1 UBE3A UBQLN1 UBQLN2 UBQLN4 UBXN6 UBXN7 USP13 USP5 VENTX VEZF1 VHLL VPS37C WDR73 WWOX WWP1 YOD1 ZBTB32 ZC3H10 ZFAND2A ZFAND2B ZFYVE9 ZNF34 ZNF581	34 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM120A FAM168A FLG IGF2BP1 IGF2BP2 IGF2BP3 LARP1 MAP3K1 MEOX1 MTDH MUL1 NEDD8 NFYC PABPC4 PAX5 PAX6 REL RNF111 RPS3 RPS3A SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 ZNRF1
Entrez ID		9802	26043
HPRD ID		08463	19396
Ensembl ID		ENSG00000183283	ENSG00000163960
Uniprot IDs		Q15038	O94888
PDB IDs			1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?		Protein Binding Polyubiquitin Modification-dependent Protein Binding Post-translational Protein Modification Ubiquitin Binding Nucleus Protein Ubiquitination Protein Modification By Small Protein Conjugation Nucleoplasm Modification-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Autophagy Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process K48-linked Deubiquitinase Activity Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Catabolic Process Cytoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Cysteine-type Deubiquitinase Activity Positive Regulation Of Metabolic Process Macroautophagy Protein K48-linked Deubiquitination Negative Regulation Of Signal Transduction Cysteine-type Peptidase Activity Protein Modification Process Ubiquitin-protein Transferase Activity Protein K63-linked Ubiquitination Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Binding Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Protein Tag Activity Protein Metabolic Process Identical Protein Binding Cytosol Autophagosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Modification By Small Protein Removal Clathrin Binding Negative Regulation Of RNA Biosynthetic Process Regulation Of Macroautophagy Establishment Of Protein Localization To Vacuole	Positive Regulation Of Macromolecule Metabolic Process MRNA 5'-UTR Binding Positive Regulation Of Metabolic Process Protein Metabolic Process Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule Protein Ubiquitination Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of Protein Metabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination CRD-mediated MRNA Stabilization N6-methyladenosine-containing RNA Reader Activity Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Base-excision Repair Macromolecule Metabolic Process Post-translational Protein Modification Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction MRNA 3'-UTR Binding Translation Regulator Activity Cytosol Regulation Of RNA Metabolic Process Regulation Of Proteolysis MRNA Stabilization Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization NF-kappaB Complex Regulation Of Base-excision Repair Positive Regulation Of Protein Metabolic Process Negative Regulation Of Translation Nucleus Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Protein Modification Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of MRNA Metabolic Process Cytoplasm Regulation Of RNA Stability Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process
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