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DAZAP2 and CDK4
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
DAZAP2
CDK4
Gene Name
DAZ associated protein 2
cyclin-dependent kinase 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cyclin-dependent Protein Kinase Holoenzyme Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytosol
Tight Junction
Nuclear Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
WW Domain Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Cyclin Binding
Protein Complex Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Lens Development In Camera-type Eye
Chromatin Organization
Protein Phosphorylation
Signal Transduction
Circadian Rhythm
Positive Regulation Of Cell Proliferation
Response To Toxic Substance
Response To Lead Ion
Regulation Of Gene Expression
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Organ Regeneration
Response To Testosterone
Response To Drug
Positive Regulation Of Apoptotic Process
Positive Regulation Of Translation
Positive Regulation Of Cell Size
Regulation Of Protein Kinase Activity
Positive Regulation Of Fibroblast Proliferation
Cell Division
Response To Hyperoxia
Negative Regulation Of Cell Cycle Arrest
Pathways
Meiotic recombination
Chromatin organization
Ubiquitin-dependent degradation of Cyclin D
Cellular Senescence
G1 Phase
Senescence-Associated Secretory Phenotype (SASP)
S Phase
Oncogene Induced Senescence
Cell Cycle, Mitotic
Ubiquitin-dependent degradation of Cyclin D1
RMTs methylate histone arginines
Cyclin D associated events in G1
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
Transcriptional regulation of white adipocyte differentiation
Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Celiac disease and Rheumatoid arthritis (
21383967
)
Protein-Protein Interactions
86 interactors:
AATF
ARID5A
ATXN1
ATXN1L
BAG3
BATF2
C1orf94
CALCOCO2
CCDC120
CDK4
CEP70
CLASRP
COL4A2
COL4A5
CXCL12
DAB1
DAZ1
DAZL
DCUN1D1
EPN1
EXD3
FAM168A
FAM46B
FAM46C
FBN3
GPSM1
HGS
HIP1
KRTAP19-5
KRTAP8-1
LASP1
LMO2
MED31
NDUFA5
NEDD4
NEDD4L
NOC4L
OPTN
OTULIN
PEF1
PLEKHB2
PLSCR1
POGZ
POLI
PRR20A
RABGEF1
RBFOX1
RBFOX2
RBPMS
RHOXF2
RNF115
RNF208
ROR2
RPS27A
SEPT2
SMAP2
SMURF2
SOX6
SQSTM1
STAM2
STAT6
TAX1BP1
TCF7L2
TEX37
TLE1
TNIP3
TOLLIP
UBA52
UBAC1
UBASH3A
UBASH3B
UBB
UBC
UBE2D4
UBE2E2
UBQLN4
USP5
VHLL
VPS37C
WDR73
WWP1
ZC3H10
ZFAND2B
ZFYVE9
ZNF34
ZNF581
90 interactors:
ANKRD12
ANXA7
APLP1
APP
ARID4A
ATP5B
BAG6
BCL11A
BIRC5
BMPR1B
BRCA1
CAMK1
CAPNS1
CCND1
CCND2
CCND3
CDC37
CDC45
CDC6
CDC7
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CDKN2C
CDKN2D
CEBPA
CIB1
CNOT7
DAZAP2
DDAH2
DUSP9
FOXM1
GLI1
H1F0
HIST1H1A
HIST1H1D
HMGXB3
HOOK1
IFI27
IL15RA
LUC7L2
MAPRE2
MARCKS
MCM2
MYC
MYOD1
MZF1
NCOA2
NOL12
ORC3
OTX2
PGD
PKM
POLD1
PPP2R1B
PRKAR1A
PSMD10
PTMA
QARS
RB1
RBL1
RBL2
RFC1
RFC4
RPL34
SENP3
SERTAD1
SETDB1
SHOX2
SKP1
SLBP
SMAD2
SMAD3
SNCA
TGFBR1
TK1
TRMT2A
TSPYL2
UBTF
UHRF2
VTA1
WDR33
ZBTB16
ZNF101
ZNF219
ZNF335
ZNF655
ZSCAN1
Entrez ID
9802
1019
HPRD ID
08463
00447
Ensembl ID
ENSG00000183283
ENSG00000135446
Uniprot IDs
E9PB45
Q15038
P11802
Q6LC83
PDB IDs
1LD2
2W96
2W99
2W9F
2W9Z
3G33
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Signal Transduction
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Signaling
Negative Regulation Of ERBB Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Viral Protein Processing
Regulation Of ERBB Signaling Pathway
Protein Ubiquitination
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Gene Expression
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Metabolic Process
Response To Transforming Growth Factor Beta
Virion Assembly
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Signaling
Intracellular Transport Of Virus
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Intracellular Receptor Signaling Pathway
RNA Metabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
RNA Biosynthetic Process
Endosomal Transport
Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Type I Interferon Production
Transforming Growth Factor Beta Receptor Signaling Pathway
Modification-dependent Protein Catabolic Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cell Cycle
Regulation Of Cell Cycle
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cell Cycle Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Kinase Activity
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Gene Expression
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Mitotic Cell Cycle
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Protein Kinase Activity
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Gene Expression
Regulation Of Cell Proliferation
Biosynthetic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cell Cycle
RNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Phosphorylation
Gene Expression
Negative Regulation Of Cell Cycle
Positive Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Phosphorylation
Chromosome Organization
Regulation Of Nucleic Acid-templated Transcription
Transcription, DNA-templated
Regulation Of RNA Biosynthetic Process
Tagcloud
?
aberrantly
acetylglucosaminyltransferase
antigens
bage
ctl
ecto
fig
fm3
fm57
gage
gp100
immunogenic
immunogenicity
in4
maa
mage
mart
melan
melanocyte
melanomas
p15
pbl
permitted
pointing
prame
ref
tab
trp
tyrosinase
uncloned
Tagcloud (Difference)
?
aberrantly
acetylglucosaminyltransferase
antigens
bage
ctl
ecto
fig
fm3
fm57
gage
gp100
immunogenic
immunogenicity
in4
maa
mage
mart
melan
melanocyte
melanomas
p15
pbl
permitted
pointing
prame
ref
tab
trp
tyrosinase
uncloned
Tagcloud (Intersection)
?