IRS2 and RPTOR

  • Number of citations of the paper that reports this interaction (PMID 19561084)
  • 10

IRS2

RPTOR

Gene Name insulin receptor substrate 2 regulatory associated protein of MTOR, complex 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SIRT1 SOCS1 SOCS3 SOCS6 SOCS7 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB
Entrez ID 8660 57521
HPRD ID 02878 06184
Ensembl ID ENSG00000185950 ENSG00000141564
Uniprot IDs Q9P084 Q9Y4H2 F5H7J5 Q6DKI0 Q8N122
PDB IDs 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
Tagcloud (Difference) ?
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
Tagcloud (Intersection) ?