IRS2 and BCL2L1

  • Number of citations of the paper that reports this interaction (PMID 10679027)
  • 8
  • Data Source:
  • HPRD (in vivo)

IRS2

BCL2L1

Gene Name insulin receptor substrate 2 BCL2-like 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SIRT1 SOCS1 SOCS3 SOCS6 SOCS7 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 79 interactors: ACTB AKT1 ANTXR1 APAF1 AVEN BAD BAG1 BAK1 BAX BBC3 BCAP31 BCL2 BCL2L10 BCL2L11 BCL2L12 BCL2L14 BCLAF1 BECN1 BID BIK BLK BMF BNIP1 BNIP3 BNIP3L BNIPL CAPN1 CASP1 CASP8 CASP9 CDKN2A CFLAR CRYAA CRYAB CYCS DOCK7 EDRF1 FBP1 FKBP8 GLOD4 HRK IKZF3 IRS1 IRS2 LARP1 MAPK8 MCL1 METTL23 MOAP1 MTOR NLRP1 PARK7 PDIA4 PLD3 PMAIP1 PPHLN1 PPP1CA PSEN1 PSEN2 PTN RAD9A RAF1 RBM5 RTN1 RTN4 SIVA1 SNCA SPNS1 TLE1 TMBIM6 TP53 TP53BP2 TPT1 UBR1 UHRF2 VDAC1 ZFYVE1 ZHX1 ZNF219
Entrez ID 8660 598
HPRD ID 02878 02497
Ensembl ID ENSG00000185950 ENSG00000171552
Uniprot IDs Q9P084 Q9Y4H2 Q07817 Q5TE63
PDB IDs 3FQW 3FQX 1BXL 1G5J 1LXL 1MAZ 1R2D 1R2E 1R2G 1R2H 1R2I 1YSG 1YSI 1YSN 2B48 2LP8 2LPC 2M03 2M04 2O1Y 2O2M 2O2N 2P1L 2PON 2YJ1 2YQ6 2YQ7 2YXJ 3CVA 3FDL 3FDM 3INQ 3IO8 3PL7 3QKD 3R85 3SP7 3SPF 3ZK6 3ZLN 3ZLO 3ZLR 4A1U 4A1W 4AQ3 4EHR 4HNJ 4IEH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
aacr  antiapoptotic  antiestrogens  aromatase  competitive  deprivation  drives  escaped  estrogen  eventually  fulvestrant  hcc1428  junb  kinome  letrozole  lted  mcf7  ovariectomized  parental  pharmacologic  plk1  polo  potently  recur  res  rnai  top  volasertib  xl 
Tagcloud (Difference) ?
adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  rescued  rtk  scc  synergistic  weakly 
antiapoptotic  antiestrogens  aromatase  competitive  deprivation  drives  escaped  estrogen  eventually  fulvestrant  hcc1428  junb  kinome  letrozole  lted  mcf7  ovariectomized  parental  pharmacologic  plk1  polo  potently  recur  rnai  top  volasertib  xl 
Tagcloud (Intersection) ?
aacr  res