RPTOR and PRKAA2

  • Number of citations of the paper that reports this interaction (PMID 18439900)
  • 479
  • Data Source:
  • BioGRID (enzymatic study)

RPTOR

PRKAA2

Gene Name regulatory associated protein of MTOR, complex 1 protein kinase, AMP-activated, alpha 2 catalytic subunit
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 48 interactors: ABI2 ACACA ACACB AES AIMP2 APPBP2 C19orf47 CCNB1IP1 EEF2K EPM2A FOS GLI1 HMBOX1 HNF4A HOMEZ KCTD1 KIF24 KIFC3 KRT31 KRTAP10-3 L3MBTL3 LEP MYOZ1 NECAB2 NONO NOTCH2NL NRAP NUTM1 PBXIP1 PFKFB2 PRKAB1 PRKAB2 PRKAG1 RBPMS RFX6 RPTOR SNW1 STK11 TCF4 TMOD1 TRIP6 TSC22D4 UBE2I USHBP1 VPS52 WWP1 ZBTB8A ZNF397
Entrez ID 57521 5563
HPRD ID 06184 02735
Ensembl ID ENSG00000141564 ENSG00000162409
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 P54646
PDB IDs 2H6D 2LTU 2YZA 3AQV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
amyloidogenesis  apmk  appswe  arc  biogenesis  functionality  igf1  igf2  igfbp2  igfr  impairments  insoluble  insr  intolerant  irs1  irs2  nrf1  oxphos  pampk  pgc  pgc1  plaque  precede  ps1  ps1de9  reinforce  sensors  tfam  thr172 
Tagcloud (Difference) ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
amyloidogenesis  apmk  appswe  arc  biogenesis  functionality  igf1  igf2  igfbp2  igfr  impairments  insoluble  insr  intolerant  irs1  irs2  nrf1  oxphos  pampk  pgc  pgc1  plaque  precede  ps1  ps1de9  reinforce  sensors  tfam  thr172 
Tagcloud (Intersection) ?