RPTOR and MAPK1

  • Number of citations of the paper that reports this interaction (PMID 21071439)
  • 39
  • Data Source:
  • BioGRID (enzymatic study, pull down, enzymatic study)

RPTOR

MAPK1

Gene Name regulatory associated protein of MTOR, complex 1 mitogen-activated protein kinase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 213 interactors: AR ARRB1 ARRB2 ATF2 ATP1A1 BCL2 BCL6 BRAF C1QBP CACYBP CAD CALCOCO1 CAPN2 CASP8 CASP9 CAV1 CD19 CDC25C CDT1 CDX2 CEBPB CEP55 CMTM3 CREBBP CRP CTSD CUEDC2 DAPK1 DUSP1 DUSP16 DUSP2 DUSP3 DUSP4 DUSP5 DUSP6 DUSP7 DUSP9 DYRK1B EGFR EGLN3 EIF4EBP1 ELK1 ENAH EP300 EPOR ERF ESR1 ESR2 ETS1 FCGR2B FHL3 FOS FOXO3 FRS2 FRS3 GAB1 GAB2 GABRR1 GAPDH GATA1 GATA2 GATA4 GJA1 GMFB GNPTAB GORASP2 GRB10 GRB2 GSK3B HDAC4 HIF1A HNF4A HSF1 HSF4 HSP90AA1 ID2 IER3 IFI35 IFNAR1 IQGAP1 IRS1 ITGB6 JUN JUND KARS KHDRBS1 KLF11 KRT8 KSR1 KSR2 LAMTOR3 LCK LIFR LIPE LRPAP1 MAFA MAP2K1 MAP2K2 MAP2K4 MAP2K6 MAP2K7 MAP3K1 MAP3K10 MAPK14 MAPK8 MAPKAPK2 MAPKAPK5 MBP MCL1 METAP2 MITF MKNK1 MKNK2 MTIF3 MTPN MYB MYC NCOA1 NCOA3 NDE1 NEFH NEK2 NGFR NKX2-1 NOXA1 NR3C1 NR4A1 NR5A1 NTRK3 NUP153 PAK1 PAK2 PDE4D PEA15 PEBP1 PLAT PLCB1 PLK3 PPARA PPARG PPP1CA PPP1R9B PPP2CA PPP2R5B PPP2R5C PRKCD PRKCE PRKCZ PRPSAP1 PTPN1 PTPN5 PTPN7 PTPRE PTPRH PTPRR PXN RAF1 RB1 RET RGS19 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KB1 RPTOR RXRA SCNN1G SH2D1A SH2D3C SHANK3 SHC1 SLC9A1 SMAD1 SMAD2 SMAD3 SMAD4 SNCA SNCG SORBS3 SOS1 SP1 SREBF1 SREBF2 STAT3 STAT5A STAT5B SUPT20H TCF3 TFCP2 TGIF1 TH TIAL1 TNFRSF1A TNFRSF25 TNFSF11 TNIP1 TNIP2 TNKS2 TOB1 TOP2A TP53 TPR TSC2 TTN UBR5 UBTF VAV1 VDR YBX1 YBX3 ZC3HC1 ZFP36
Entrez ID 57521 5594
HPRD ID 06184 01496
Ensembl ID ENSG00000141564 ENSG00000100030
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 P28482 Q1HBJ4 Q499G7
PDB IDs 1PME 1TVO 1WZY 2OJG 2OJI 2OJJ 2Y9Q 3D42 3D44 3I5Z 3I60 3SA0 3TEI 3W55 4FMQ 4FUX 4FUY 4FV0 4FV1 4FV2 4FV3 4FV4 4FV5 4FV6 4FV7 4FV8 4FV9 4G6N 4G6O 4H3P 4H3Q 4IZ5 4IZ7 4IZA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
ac  analysing  bioinformatics  boolean  david  hijacks  host  ikka  ikkb  ikky  interrupts  intersected  jean  knockouts  logical  lose  manchester  marc  modelling  motivation  perturbation  perturbs  replicate  reproduced  robertson  schwartz  silico  supplementary  uk 
Tagcloud (Difference) ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
ac  analysing  bioinformatics  boolean  david  hijacks  host  ikka  ikkb  ikky  interrupts  intersected  jean  knockouts  logical  lose  manchester  marc  modelling  motivation  perturbation  perturbs  replicate  reproduced  robertson  schwartz  silico  supplementary  uk 
Tagcloud (Intersection) ?