RPTOR and EIF4EBP1

  • Number of citations of the paper that reports this interaction (PMID 12150926)
  • 316
  • Data Source:
  • HPRD (in vitro, in vivo)

RPTOR

EIF4EBP1

Gene Name regulatory associated protein of MTOR, complex 1 eukaryotic translation initiation factor 4E binding protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 32 interactors: AKT1 ATM BUB1 CHTF8 CSNK2A1 CSNK2A2 EIF4E EIF4E2 GSK3B IRAK4 LATS1 LRRK2 MAPK1 MAPK14 MAPKAP1 MAPKAPK5 MLST8 MTOR MVD PPP2CA PPP2R4 PRKCA PRKDC REL RHEBL1 RICTOR RORC RPS6KA5 RPS6KB1 RPTOR STK3 TCF4
Entrez ID 57521 1978
HPRD ID 06184 03746
Ensembl ID ENSG00000141564 ENSG00000187840
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 Q13541
PDB IDs 1WKW 2JGB 2JGC 2V8W 2V8X 2V8Y 3HXG 3HXI 3M93 3M94 3U7X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
autophagy  bcl2  birc5  buffer  constituents  damaged  dataset  degrades  deregulation  distant  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Difference) ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
autophagy  bcl2  birc5  buffer  constituents  damaged  dataset  degrades  deregulation  distant  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Intersection) ?