RPTOR and MTOR

  • Number of citations of the paper that reports this interaction (PMID 12150925)
  • 554
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique)
  • HPRD (in vitro, in vivo)

RPTOR

MTOR

Gene Name regulatory associated protein of MTOR, complex 1 mechanistic target of rapamycin (serine/threonine kinase)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 42 interactors: AKT1 AKT1S1 AMBRA1 BCL2L1 C7orf25 CDC37 CFP CLIP1 EIF3F EIF4EBP1 EIF4EBP2 FKBP1A FKBP8 GPHN GSK3B IRS1 MAF1 MLST8 PA2G4 PDPK1 PLD2 PPP2R2A PREX1 PRKAA1 PRKCA PRR5L RHEB RHEBL1 RICTOR RPS6KA1 RPS6KB1 RPS6KB2 RPTOR RRAGB RRAGD SEPT2 STAT3 TELO2 TERT TRAF6 UBQLN1 YWHAQ
Entrez ID 57521 2475
HPRD ID 06184 03134
Ensembl ID ENSG00000141564 ENSG00000198793
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 B4DZD5 P42345
PDB IDs 1AUE 1FAP 1NSG 2FAP 2GAQ 2NPU 2RSE 3FAP 4DRH 4DRI 4DRJ 4FAP 4JSN 4JSP 4JSV 4JSX 4JT5 4JT6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
Tagcloud (Difference) ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  reliant  rictor  sclerosis  tsc1  tuberous 
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
Tagcloud (Intersection) ?
rapamycin