RPTOR and RHEB

  • Number of citations of the paper that reports this interaction (PMID 15854902)
  • 168
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

RPTOR

RHEB

Gene Name regulatory associated protein of MTOR, complex 1 Ras homolog enriched in brain
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 22 interactors: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF ECSIT FKBP8 MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RPS6KB1 RPTOR TSC1 TSC2
Entrez ID 57521 6009
HPRD ID 06184 03188
Ensembl ID ENSG00000141564 ENSG00000106615
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 Q15382
PDB IDs 1XTQ 1XTR 1XTS 3SEA 3T5G
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Difference) ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  reliant  rictor  sclerosis  tsc1 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  neoplasms  pathologies  phenomena  salirasib  sirolimus  sporadic  trans  tsc  tsc2  yielded 
Tagcloud (Intersection) ?
mtorc1  rapamycin  tuberous