RPTOR and RPS6KB1

  • Number of citations of the paper that reports this interaction (PMID 12150926)
  • 316
  • Data Source:
  • HPRD (in vitro)

RPTOR

RPS6KB1

Gene Name regulatory associated protein of MTOR, complex 1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: AKT1S1 EIF4EBP1 ICK IRS1 IRS2 MAPK1 MAPK3 MARK4 MLST8 MTOR PLD2 PRKAA1 PRKAA2 PRR5L RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB 54 interactors: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B DPPA4 EEF2K EIF4B EIF4EBP1 EP300 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MLST8 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RICTOR RPS6 RPTOR SRC STK11 SYK TERT TRAF4 URI1 XPO1
Entrez ID 57521 6198
HPRD ID 06184 10202
Ensembl ID ENSG00000141564 ENSG00000108443
Uniprot IDs F5H7J5 Q6DKI0 Q8N122 B2R779 B4DLT4 B4DTG1 F6UYM1 P23443 Q7Z721
PDB IDs 3A60 3A61 3A62 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ablation  balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  mtorc1  mtorc2  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  rictor  sclerosis  tsc1  tuberous 
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
Tagcloud (Difference) ?
balanced  cns  complexes  contributions  delicately  functionally  hypomyelination  integrates  lipogenesis  lipogenic  minor  mtor  myelin  myelination  oligodendrocyte  oligodendrocytes  overactivation  overtones  practical  rapamycin  reliant  sclerosis  tsc1  tuberous 
70kda  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  nonsenescent  polypeptide  prkaa  replicative  s6k1  senescent  ureahydrolase  wk 
Tagcloud (Intersection) ?
ablation  mtorc1  mtorc2  rictor