PIAS1 and MDC1

  • Number of citations of the paper that reports this interaction (PMID 22661230)
  • 32
  • Data Source:
  • BioGRID (enzymatic study)

PIAS1

MDC1

Gene Name protein inhibitor of activated STAT, 1 mediator of DNA-damage checkpoint 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 92 interactors: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CARM1 CASP8 CBS CEBPA CEBPE CHUK CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 ESR1 ESR2 FLI1 GATA4 GLUL GRM8 HIC1 HTT JUN L3MBTL2 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRMT1 PRMT6 PRPF40A PTK2 PTPN1 RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SIAH1 SIAH2 SKIL SMAD1 SMAD4 SMAD7 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO2 SUMO3 TBP TP53 TP73 TRIM27 TRIM55 TRIM63 UBE2I YWHAZ ZNF451 ZNF76 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251
Entrez ID 8554 9656
HPRD ID 16029 16252
Ensembl ID ENSG00000033800 ENSG00000137337
Uniprot IDs O75925 Q1XBU8 A1Z5I9 Q14676
PDB IDs 1V66 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
akap6  atf7  atxn1  bmpr2  categorize  deltan  eef1a1  grip2  gtf2f1  interactors  jbd  jbds  jnk1alpha1  jnk3  jnk3alpha1  jnks  kcne4  myo9b  nnat  ptgds  ptpn2  rabgap1  rusc2  shank1  sumo1  sypl1  tkt  topbp1  znf668 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Difference) ?
akap6  atf7  atxn1  bmpr2  categorize  deltan  eef1a1  grip2  gtf2f1  interactors  jbd  jbds  jnk1alpha1  jnk3  jnk3alpha1  jnks  kcne4  myo9b  nnat  ptgds  ptpn2  rabgap1  rusc2  shank1  sumo1  sypl1  tkt  topbp1  znf668 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Intersection) ?