RAB2B and ADAMTSL4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RAB2B	ADAMTSL4
Gene Name		RAB2B, member RAS oncogene family	ADAMTS-like 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Plasma Membrane Extracellular Vesicular Exosome	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function	GTPase Activity GTP Binding GDP Binding	Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS			Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		9 interactors: ADAMTSL4 APP BLZF1 FAM114A1 FAM71C GOLGA2 ICA1 SMAD1 SMAD4	106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587
Entrez ID		84932	54507
HPRD ID		06312	18237
Ensembl ID		ENSG00000129472	ENSG00000143382
Uniprot IDs		B4DUD4 Q6NZ33 Q8WUD1	F8WAD0 Q6UY14 Q9UFG7
PDB IDs		2A5J
Enriched GO Terms of Interacting Partners?		SMAD Protein Complex Assembly Regulation Of Binding BMP Signaling Pathway Embryonic Pattern Specification Growth Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Regulation Of Growth Synaptic Growth At Neuromuscular Junction Nephrogenic Mesenchyme Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Mesoderm Development Regulation Of Protein Binding Collateral Sprouting In Absence Of Injury Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Kidney Epithelium Development Cell Proliferation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Gastrulation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cell Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Endocardial Cell Differentiation Primary MiRNA Processing Axon Choice Point Recognition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Osteoblast Fate Commitment Positive Regulation Of Transcription From RNA Polymerase II Promoter Formation Of Anatomical Boundary Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Endothelial Cell Activation Neuron Remodeling Regulation Of Transforming Growth Factor Beta2 Production Developmental Growth Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Cell Fate Commitment Protein O-linked Fucosylation Kidney Development Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation	Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		amplify annotated bv ccl5 cd80 chemokines cinnamomi cr cutoff cxcl10 cyclooxygenase grin2a ifi203 ifit1 il1alpha il6 imply inos lilrb3 lps microglia microglial nos2 periphery ramulus rsad2 supplemental table vpreb1	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		amplify annotated bv ccl5 cd80 chemokines cinnamomi cr cutoff cxcl10 cyclooxygenase grin2a ifi203 ifit1 il1alpha il6 imply inos lilrb3 lps microglia microglial nos2 periphery ramulus rsad2 supplemental table vpreb1	abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?