RAB2B and FAM114A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAB2B	FAM114A2
Description		RAB2B, member RAS oncogene family	family with sequence similarity 114 member A2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding Purine Nucleotide Binding
	Biological Process	Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Exocytosis Defense Response To Virus
Pathways		RAB geranylgeranylation	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Height ( 31562340)	Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 28957414 32888494)
Interacting Genes		20 interacting genes: ADAMTSL4 APP BLZF1 CRK FAM114A1 FAM114A2 GARIN4 GARIN6 GOLGA2 ICA1 MEOX2 NOP2 SGSM2 SMAD1 SMAD4 SRSF11 STAMBPL1 TBX19 TXNDC11 VRTN	11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA
Entrez ID		84932	10827
HPRD ID		06312	12831
Ensembl ID		ENSG00000129472	ENSG00000055147
Uniprot IDs		B4DUD4 Q8WUD1	A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5
PDB IDs		2A5J
Enriched GO Terms of Interacting Partners?		Heteromeric SMAD Protein Complex Embryonic Pattern Specification SMAD Protein Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Yeast I-SMAD Binding Cardiac Conduction System Development Cellular Response To Growth Factor Stimulus Golgi Organization SMAD Protein Signal Transduction	Autophagosome Membrane Regulation Of Amyloid-beta Clearance Cytoplasmic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Membrane Negative Regulation Of Establishment Of Blood-brain Barrier Mitochondrial MRNA Processing Protein Localization To Vacuolar Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Apparatus Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Autophagy Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Positive Regulation Of Membrane Tubulation
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