RAB2B and FAM114A1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		RAB2B	FAM114A1
Description		RAB2B, member RAS oncogene family	family with sequence similarity 114 member A1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Exocytosis Defense Response To Virus	Heart Valve Morphogenesis Inflammatory Response Gene Expression Fibroblast Migration Angiotensin-activated Signaling Pathway Fibroblast Proliferation Tissue Remodeling Fibroblast Activation Connective Tissue Replacement
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Height ( 31562340)	Alcohol dependence ( 24166409) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Helicobacter pylori serologic status ( 23652523) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643)
Interacting Genes		20 interacting genes: ADAMTSL4 APP BLZF1 CRK FAM114A1 FAM114A2 GARIN4 GARIN6 GOLGA2 ICA1 MEOX2 NOP2 SGSM2 SMAD1 SMAD4 SRSF11 STAMBPL1 TBX19 TXNDC11 VRTN	9 interacting genes: AGTRAP CMTM5 GDAP1 RAB2A RAB2B SNAPIN SPG21 TNFRSF10D TNS2
Entrez ID		84932	92689
HPRD ID		06312	11282
Ensembl ID		ENSG00000129472	ENSG00000197712
Uniprot IDs		B4DUD4 Q8WUD1	Q8IWE2
PDB IDs		2A5J
Enriched GO Terms of Interacting Partners?		Heteromeric SMAD Protein Complex Embryonic Pattern Specification SMAD Protein Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Yeast I-SMAD Binding Cardiac Conduction System Development Cellular Response To Growth Factor Stimulus Golgi Organization SMAD Protein Signal Transduction	Acrosomal Vesicle Organelle Fusion Golgi Membrane Golgi Apparatus Membrane Autophagosome Membrane Positive Regulation Of Late Endosome To Lysosome Transport Cytoplasmic Vesicle Vesicle Fusion Organelle Membrane Fusion Golgi Organization
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