MAP1LC3A and MAP1A

Number of citations of the paper that reports this interaction (PMID 7908909)
51

Data Source:
HPRD (in vivo, in vitro)

		MAP1LC3A	MAP1A
Gene Name		microtubule-associated protein 1 light chain 3 alpha	microtubule-associated protein 1A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Cytosol Microtubule Microtubule Associated Complex
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Microtubule Cytoskeleton Organization Sensory Perception Of Sound
Pathways
Drugs			Estramustine
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	22 interactors: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 SPP1 TUBA4A TUBB UPF2
Entrez ID		84557	4130
HPRD ID		03144	02549
Ensembl ID		ENSG00000101460	ENSG00000166963
Uniprot IDs		Q9H492	E9PGC8 P78559 Q504X9
PDB IDs		3ECI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Movement Of Cell Or Subcellular Component Cellular Localization Receptor Localization To Synapse Response To External Stimulus Cytoskeleton Organization Axonogenesis Axon Development Protein Localization To Synapse Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Platelet Activation Cell-cell Signaling Developmental Process Axon Guidance Neuron Projection Morphogenesis Muscle Contraction Blood Coagulation Hemostasis Cell Morphogenesis Involved In Differentiation Muscle System Process Establishment Of Localization In Cell Generation Of Neurons Neuron Projection Development Response To Stimulus Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Locomotion Multicellular Organismal Development Regulation Of Body Fluid Levels Cell Differentiation Synaptic Transmission Wound Healing System Development Nervous System Development Receptor Clustering Transport Neuron Development Cell Development Smooth Muscle Contraction Nucleotide Phosphorylation Establishment Or Maintenance Of Cell Polarity Cell Activation MRNA Export From Nucleus Cytoplasmic Transport Cellular Metal Ion Homeostasis Response To Wounding Cell Morphogenesis Organelle Organization Intracellular Transport
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Difference) ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Intersection) ?