MAP1LC3A and KIF15

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAP1LC3A	KIF15
Gene Name		microtubule-associated protein 1 light chain 3 alpha	kinesin family member 15
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Centrosome Spindle Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Membrane
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	DNA Binding Motor Activity Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Microtubule-based Movement Mitotic Nuclear Division Blood Coagulation Metabolic Process Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	5 interactors: CHD3 KIAA1377 MAP1LC3A MKI67 VIM
Entrez ID		84557	56992
HPRD ID		03144	10037
Ensembl ID		ENSG00000101460	ENSG00000163808
Uniprot IDs		Q9H492	Q9NS87
PDB IDs		3ECI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Organelle Organization Spindle Organization Cytoskeleton Organization Bergmann Glial Cell Differentiation Cell Cycle Microtubule Cytoskeleton Organization Cellular Response To Nitrogen Starvation Intermediate Filament Organization Organelle Assembly Lens Fiber Cell Development Nucleophagy Astrocyte Development Mitochondrion Degradation Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Organelle Disassembly Cytoplasmic Microtubule Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Mitotic Spindle Organization Autophagic Vacuole Assembly Intermediate Filament-based Process Actin-mediated Cell Contraction Microtubule-based Process
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	accumulates bundles crosslink cytoskeleton dimeric enable enabling fibers harbors inherent kinesin kinetochore loads localizes microtubules mt mts nonmotor onto recognize recognizes repressed rigorously slide speculated spindle subsets tpx2 unfolding
Tagcloud (Difference) ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	accumulates bundles crosslink cytoskeleton dimeric enable enabling fibers harbors inherent kinesin kinetochore loads localizes microtubules mt mts nonmotor onto recognize recognizes repressed rigorously slide speculated spindle subsets tpx2 unfolding
Tagcloud (Intersection) ?