MAP1LC3A and RABGAP1L

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (pull down)

		MAP1LC3A	RABGAP1L
Gene Name		microtubule-associated protein 1 light chain 3 alpha	RAB GTPase activating protein 1-like
Image
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleus Early Endosome Golgi Apparatus
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	Rab GTPase Activator Activity Rab GTPase Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Positive Regulation Of Rab GTPase Activity Regulation Of Protein Localization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	5 interactors: GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36
Entrez ID		84557	9910
HPRD ID		03144	16464
Ensembl ID		ENSG00000101460	ENSG00000152061
Uniprot IDs		Q9H492	B7ZAP0 F1LJ00 Q5R372 Q9Y3L8
PDB IDs		3ECI	3HZJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Rab Protein Signal Transduction Vacuole Organization Membrane Fusion Nucleophagy Ras Protein Signal Transduction Membrane Organization Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Organelle Assembly Establishment Of Protein Localization To Plasma Membrane Small GTPase Mediated Signal Transduction Cellular Component Assembly Trans-Golgi Network To Recycling Endosome Transport Cellular Response To Starvation Protein Localization To Plasma Membrane Protein Localization To Cell Leading Edge Autophagy Intracellular Protein Transport Cellular Response To Nutrient Levels Response To Starvation Phagosome-lysosome Fusion Cellular Response To Extracellular Stimulus Cell Communication Plasma Membrane Organization Establishment Of Protein Localization To Membrane Protein Kinase A Signaling Establishment Of Sertoli Cell Barrier Organelle Organization Cellular Protein Localization Cellular Response To Stimulus Protein Transport Establishment Of Protein Localization Protein Localization To Membrane Intracellular Transport Mitochondrion Organization Phagolysosome Assembly Endothelial Cell Chemotaxis Response To Nutrient Levels Endomembrane System Organization Cellular Response To Nitrogen Starvation Response To Extracellular Stimulus Response To External Stimulus Intracellular Signal Transduction Sertoli Cell Development Protein Localization Golgi To Plasma Membrane Protein Transport Endocytic Recycling Response To Stimulus
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	actionable arid1a bicc1 brca2 cdk6 cdkn2a cholangiocarcinoma curable erbb3 extrapolated featured fgfr2 fusions harbored icc idh1 intrahepatic introns kiaa1598 mcl1 nf1 nontargeted nras ntrk1 personalize ptch1 rearranged tacc3 thirds
Tagcloud (Difference) ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	actionable arid1a bicc1 brca2 cdk6 cdkn2a cholangiocarcinoma curable erbb3 extrapolated featured fgfr2 fusions harbored icc idh1 intrahepatic introns kiaa1598 mcl1 nf1 nontargeted nras ntrk1 personalize ptch1 rearranged tacc3 thirds
Tagcloud (Intersection) ?