MAP1LC3A and MAP1S

Number of citations of the paper that reports this interaction (PMID 21262964)
15

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		MAP1LC3A	MAP1S
Gene Name		microtubule-associated protein 1 light chain 3 alpha	microtubule-associated protein 1S
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleus Nucleolus Cytoplasm Spindle Cytosol Microtubule Cell Junction Dendrite Cell Projection Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	DNA Binding Deoxyribonuclease Activity Protein Binding Microtubule Binding Tubulin Binding Identical Protein Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Microtubule Bundle Formation Apoptotic DNA Fragmentation Nervous System Development Brain Development Mitochondrion Transport Along Microtubule Neuron Projection Morphogenesis Execution Phase Of Apoptosis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	10 interactors: BPY2 BPY2C HDAC4 LRPPRC MAP1LC3A PIN1 RASSF1 RASSF5 SLC2A4 SOCS3
Entrez ID		84557	55201
HPRD ID		03144	10461
Ensembl ID		ENSG00000101460	ENSG00000130479
Uniprot IDs		Q9H492	B4DH53 Q66K74
PDB IDs		3ECI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Positive Regulation Of Protein Ubiquitination Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Amylopectin Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Response To Stress Positive Regulation Of Protein Metabolic Process Single Fertilization Spongiotrophoblast Differentiation Fertilization Response To Cytokine Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Glucose Import
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	adenocarcinomas autophagic autophagosomal autophagy biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc lrpprc map1a map1b microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley
Tagcloud (Difference) ?		acquiring adenocarcinoma became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	adenocarcinomas autophagic autophagosomal biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc lrpprc map1a map1b microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley
Tagcloud (Intersection) ?		autophagy