MAP1LC3A and TBC1D9

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (pull down)

		MAP1LC3A	TBC1D9
Gene Name		microtubule-associated protein 1 light chain 3 alpha	TBC1 domain family, member 9 (with GRAM domain)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	Rab GTPase Activator Activity Calcium Ion Binding Protein Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Positive Regulation Of Rab GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	4 interactors: GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B
Entrez ID		84557	23158
HPRD ID		03144	11115
Ensembl ID		ENSG00000101460	ENSG00000109436
Uniprot IDs		Q9H492	Q6ZT07
PDB IDs		3ECI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Mitochondrion Organization Response To Nutrient Levels Response To Extracellular Stimulus Organelle Assembly Membrane Organization Cellular Response To Stress Catabolic Process Response To External Stimulus Cellular Component Assembly Organelle Organization Response To Stress Cell Communication Positive Regulation Of ATPase Activity Cellular Response To Stimulus Regulation Of ATPase Activity Intra-Golgi Vesicle-mediated Transport Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Response To Stimulus Negative Regulation Of Protein Catabolic Process
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	affinities appeared carcinomas companion diagnostics differences egf er esr1 female females gender genders il6st lrba male males nat1 neu pathological pgr plk1 pr products prognosis rabep1 represents share therapeutics
Tagcloud (Difference) ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	affinities appeared carcinomas companion diagnostics differences egf er esr1 female females gender genders il6st lrba male males nat1 neu pathological pgr plk1 pr products prognosis rabep1 represents share therapeutics
Tagcloud (Intersection) ?