MAP1LC3A and TBC1D7

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (pull down)

		MAP1LC3A	TBC1D7
Gene Name		microtubule-associated protein 1 light chain 3 alpha	TBC1 domain family, member 7
Image
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Cytoplasmic Membrane-bounded Vesicle Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of Rab GTPase Activity Activation Of Rho GTPase Activity Response To Growth Factor Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A	16 interactors: APP BLZF1 GABARAPL1 HOOK1 IKBKG KRT19 LDOC1 LZTS2 MAP1LC3A NEDD4 NEDD4L RPGRIP1 SSNA1 TRAF4 TSC1 TSC2
Entrez ID		84557	51256
HPRD ID		03144	18165
Ensembl ID		ENSG00000101460	ENSG00000145979
Uniprot IDs		Q9H492	Q5JPB9 Q9P0N9
PDB IDs		3ECI	3QWL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation	Establishment Of Localization In Cell Intracellular Transport Cytoplasmic Transport Cellular Localization Glucose Import Negative Regulation Of Sodium Ion Transport Vacuole Organization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Size Negative Regulation Of Signaling Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Protein Kinase Activity Nucleophagy Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Component Assembly Regulation Of Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Potassium Ion Transmembrane Transporter Activity Response To Stimulus Mitochondrion Degradation Regulation Of Signal Transduction Negative Regulation Of TOR Signaling Membrane Organization Cell Communication Synapse Organization NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Organelle Assembly Regulation Of Protein Metabolic Process Organ Development Regulation Of Potassium Ion Transmembrane Transport Intracellular Receptor Signaling Pathway Organelle Disassembly Negative Regulation Of Insulin Receptor Signaling Pathway Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Signaling Autophagic Vacuole Assembly Viral Process Cell Surface Receptor Signaling Pathway Lysosomal Transport Regulation Of Protein Phosphorylation Neuromuscular Junction Development Regulation Of TOR Signaling Macroautophagy Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cell Junction Assembly Cellular Response To Stimulus Cell Projection Organization
Tagcloud ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Difference) ?		acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Intersection) ?