MAP1LC3A and RABGAP1

Number of citations of the paper that reports this interaction (PubMedID 22354992)
55

Data Source:
BioGRID (pull down)

		MAP1LC3A	RABGAP1
Description		microtubule associated protein 1 light chain 3 alpha	RAB GTPase activating protein 1
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GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Late Endosome Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Autolysosome Synapse Glutamatergic Synapse	Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Associated Complex
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	GTPase Activator Activity Protein Binding Tubulin Binding Small GTPase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation JNK Cascade Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Response To Nutrient Levels Cellular Response To Amino Acid Starvation P38MAPK Cascade SMAD Protein Signal Transduction Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Cellular Response To Oxygen-glucose Deprivation Autophagosome Maturation	Regulation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	TBC/RABGAPs
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Birth weight ( 31043758) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 30578418) Systolic blood pressure ( 27841878)
Interacting Genes		100 interacting genes: ABTB3 AKAP13 AMBRA1 ANK2 ANK3 ANKRD62 AP5B1 APOBR APP APPL1 ARHGAP6 ATF7IP2 ATG13 ATG2A ATG4B ATG7 ATXN3 BCL9 BNIP3L BRD9 CAMSAP1 CARS2 CCPG1 CDC37 CSAG1 DPPA4 DVL2 EPHA7 FUNDC1 GPSM1 HTATSF1 IRGQ IRS4 KIF15 KXD1 LINC00696 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG MRTFA MTX1 MYBPC1 NBR1 NCOR1 NEDD4 NEDD4L NEK9 NEURL4 OPRM1 OPTN PCNT PHB1 PIAS4 PRPF40A RABGAP1 RABGAP1L RASAL3 RDH12 RELB RESF1 RETREG3 RIC1 RTKN RTN3 SEC62 SLA2 SP1 SP3 SRPK1 STBD1 STK10 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TMEM132C TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM25 TRIM32 TTN TUBA4A VPS9D1 ZBTB48 ZKSCAN4 ZNF304	10 interacting genes: CARM1 DISC1 GABARAPL1 MAP1LC3A RAB4A RAB6A RAB6B SENP1 SENP5 STAT3
Entrez ID		84557	23637
HPRD ID		03144	06575
Ensembl ID		ENSG00000101460	ENSG00000011454
Uniprot IDs		Q9H492	B7Z2B4 Q9Y3P9
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE 7R9W 7R9Z 7RA0 8T2L 8T35 8T36 8T4T	4NC6
Enriched GO Terms of Interacting Partners?		Autophagosome GTPase Activator Activity Regulation Of Cilium Assembly Autophagy Macroautophagy Positive Regulation Of Catabolic Process Positive Regulation Of Autophagy Regulation Of Organelle Assembly Autophagosome Assembly Regulation Of Cell Projection Organization Autophagosome Organization Regulation Of Cell Projection Assembly Cytoplasmic Vesicle Regulation Of Autophagy Regulation Of Plasma Membrane Bounded Cell Projection Organization Autophagy Of Mitochondrion Organelle Organization Cytosol Vacuole Organization Mitophagy Positive Regulation Of Macroautophagy Regulation Of Macroautophagy Regulation Of Cellular Component Organization Piecemeal Microautophagy Of The Nucleus Regulation Of Organelle Organization Microautophagy Nucleophagy Positive Regulation Of Metabolic Process Substrate Localization To Autophagosome M Band Cytoskeleton Organization Phagophore Assembly Site Vesicle-mediated Transport Transcription Repressor Complex Intracellular Protein Localization Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Microtubule Associated Complex Regulation Of Protein Localization Negative Regulation Of Viral Process Catabolic Process Protein Kinase Regulator Activity Suppression Of Viral Release By Host Regulation Of Viral Process Regulation Of GTPase Activity Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Catabolic Process Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity	Glutamatergic Synapse Protein Localization To Golgi Membrane Cellular Response To Nitrogen Starvation SUMO-specific Endopeptidase Activity Protein Desumoylation DeSUMOylase Activity Ciliary Basal Body Phosphatidylethanolamine Binding Myosin V Binding Protein Localization To Golgi Apparatus Presynaptic Cytosol Postsynaptic Cytosol Intra-Golgi Vesicle-mediated Transport Protein Localization To Organelle Endomembrane System Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Regulation Of Erythrocyte Differentiation Autophagosome Maturation Protein Sumoylation Autophagosome Membrane Mitophagy Peptidyl-cysteine Methylation GTPase Activity Microtubule Autophagy Of Mitochondrion Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome GTP Binding Cytoplasmic Vesicle Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Histone H3R2 Methyltransferase Activity Histone H3R17 Methyltransferase Activity Autophagosome Hydrolase Activity Antigen Processing And Presentation Retrograde Transport, Endosome To Golgi Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Histone Arginine N-methyltransferase Activity Autophagosome Organization Autophagosome Assembly Pyramidal Neuron Migration To Cerebral Cortex Central Region Of Growth Cone Regulation Of Definitive Erythrocyte Differentiation Intracellular Protein Localization Positive Regulation Of MRNA Catabolic Process Protein Modification By Small Protein Removal Phospholipid Binding Minus-end-directed Organelle Transport Along Microtubule
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