LCOR and KLF6

Number of citations of the paper that reports this interaction (PMID 22277651)
3

Data Source:
BioGRID (pull down)

		LCOR	KLF6
Gene Name		ligand dependent nuclear receptor corepressor	Kruppel-like factor 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding	DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Asthma (bronchodilator response) ( 23508266)
Protein-Protein Interactions		12 interactors: AR CTBP1 CTBP2 ESR1 GOLGA2 HDAC1 HDAC3 HDAC4 HDAC6 KLF6 TRAF1 VDR	16 interactors: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53
Entrez ID		84458	1316
HPRD ID		07609	03632
Ensembl ID		ENSG00000196233	ENSG00000067082
Uniprot IDs		Q96JN0	D3GC14 Q99612
PDB IDs		2COB
Enriched GO Terms of Interacting Partners?		Histone H4 Deacetylation Histone H3 Deacetylation Histone H3-K9 Modification Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Histone Modification Transcription Initiation From RNA Polymerase II Promoter Mammary Gland Branching Involved In Pregnancy Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Cell Proliferation Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Chromosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Biosynthetic Process Peptidyl-lysine Deacetylation Regulation Of Oxidoreductase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Substance	Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Fluid Shear Stress Chromatin Organization Gene Expression Regulation Of RNA Metabolic Process Regulation Of DNA Replication Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Component Assembly RRNA Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Notch Signaling Pathway Protein Import Into Nucleus, Translocation Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Histone H3-K9 Modification Transcription, DNA-templated Response To Fluid Shear Stress RNA Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Chromatin Modification Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Growth Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Neuron Apoptotic Process Negative Regulation Of Signaling Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process
Tagcloud ?		addresses boxes broadly copr1 coregulator coregulators corepressor corepressors corner cornr deacetylases holds mta1 nr nrs nsd1 pathophysiological potentiate prame prevailing rea recruit rely rip140 shedding silence subdivided utilizes xenobiotic	allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic
Tagcloud (Difference) ?		addresses boxes broadly copr1 coregulator coregulators corepressor corepressors corner cornr deacetylases holds mta1 nr nrs nsd1 pathophysiological potentiate prame prevailing rea recruit rely rip140 shedding silence subdivided utilizes xenobiotic	allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic
Tagcloud (Intersection) ?