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KLF6 and PNO1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
KLF6
PNO1
Description
KLF transcription factor 6
partner of NOB1 homolog
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Small-subunit Processome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Nucleic Acid Binding
RNA Binding
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
B Cell Differentiation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Ribosomal Small Subunit Biogenesis
Pathways
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Asthma (bronchodilator response) (
23508266
)
Coronary artery calcification (
23870195
)
Diastolic blood pressure (
27841878
)
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Heel bone mineral density (
28869591
30598549
)
Height (
33713608
)
Monocyte count (
32888494
)
Monocyte percentage of white cells (
32888494
)
Multiple sclerosis (
31604244
)
Plasma anti-thyroglobulin levels (
29678681
)
Red blood cell count (
32888494
)
Interacting Genes
16 interacting genes:
APOM
APP
CELSR2
EHMT2
FBL
GTF3C1
HDAC3
KLF4
LCOR
NOP56
NUFIP1
PNO1
POLA2
SP1
TAF9
TP53
10 interacting genes:
ATP5F1C
FRZB
GSTP1
IGFBP5
KLF6
PDPK1
PICK1
RXRG
SGSM2
SUPT5H
Entrez ID
1316
56902
HPRD ID
03632
14250
Ensembl ID
ENSG00000067082
ENSG00000115946
Uniprot IDs
D3GC14
Q99612
Q9NRX1
PDB IDs
6G18
6G4S
6G4W
6G51
6G53
6G5I
6ZUO
6ZXD
6ZXE
7MQ8
7MQ9
7MQA
7WTS
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
8ZDC
8ZDD
Enriched GO Terms of Interacting Partners
?
Pre-snoRNP Complex
Histone Deacetylase Binding
Nucleoplasm
DNA Binding
Box C/D Methylation Guide SnoRNP Complex
RNA Metabolic Process
Transcription Corepressor Binding
Chromatin Remodeling
Positive Regulation Of Neuron Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Small-subunit Processome
TFIID-class Transcription Factor Complex Binding
Ribosomal Small Subunit Biogenesis
DNA-templated Transcription
Transcription Repressor Complex
Box C/D SnoRNP Assembly
P53 Binding
Promoter-specific Chromatin Binding
Regulation Of MiRNA Transcription
Nucleus
Chromatin Organization
Regulation Of MiRNA Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
ATPase Binding
RRNA Metabolic Process
C2H2 Zinc Finger Domain Binding
Cellular Response To Oxygen-containing Compound
Low-density Lipoprotein Particle
Nucleobase-containing Compound Biosynthetic Process
Transcription Cis-regulatory Region Binding
Histone Methyltransferase Binding
Epigenetic Regulation Of Gene Expression
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Nucleolus
Ubiquitin-specific Protease Binding
Very-low-density Lipoprotein Particle
Negative Regulation Of Transcription By RNA Polymerase II
SnoRNA Binding
Nucleic Acid Metabolic Process
High-density Lipoprotein Particle
RRNA Transcription
Regulation Of RNA Metabolic Process
Molecular Function Activator Activity
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Lipoprotein Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Cellular Developmental Process
Negative Regulation Of Hepatocyte Differentiation
Negative Regulation Of Growth
Cell Development
Cellular Response To Epidermal Growth Factor Stimulus
Negative Regulation Of Smooth Muscle Cell Migration
Negative Regulation Of Smooth Muscle Cell Proliferation
Dinitrosyl-iron Complex Binding
S-nitrosoglutathione Binding
Response To Epidermal Growth Factor
Nitric Oxide Storage
Negative Regulation Of Muscle Hypertrophy
Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Skeletal Muscle Hypertrophy
3-phosphoinositide-dependent Protein Kinase Activity
Glial Cell Development
Regulation Of Cartilage Development
Regulation Of Smooth Muscle Cell Migration
Response To Peptide Hormone
Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Cell Migration
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
TRAF2-GSTP1 Complex
DSIF Complex
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Cellular Response To Insulin Stimulus
Regulation Of Cell Growth
Insulin-like Growth Factor Binding Protein Complex
Regulation Of Cell Population Proliferation
Regulation Of Cell Migration
Glutathione Derivative Biosynthetic Process
Cellular Response To Cell-matrix Adhesion
Insulin-like Growth Factor Ternary Complex
Membrane Curvature Sensor Activity
Epithelial Cell Development
Convergent Extension Involved In Organogenesis
Regulation Of Cell Motility
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Nitric Oxide Binding
Response To L-ascorbic Acid
Mammary Gland Involution
Positive Regulation Of Sarcomere Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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