KLF6 and APOM

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KLF6	APOM
Gene Name		Kruppel-like factor 6	apolipoprotein M
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Integral Component Of Plasma Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle High-density Lipoprotein Particle Discoidal High-density Lipoprotein Particle Spherical High-density Lipoprotein Particle Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Metal Ion Binding	Lipid Transporter Activity Phospholipid Binding Antioxidant Activity
	Biological Process	Transcription, DNA-templated Cytokine-mediated Signaling Pathway B Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Response To Glucose Cholesterol Efflux High-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Clearance Negative Regulation Of Plasma Lipoprotein Particle Oxidation Lipoprotein Metabolic Process Cholesterol Homeostasis Reverse Cholesterol Transport
Pathways
Drugs
Diseases
GWAS		Asthma (bronchodilator response) ( 23508266)	Lung adenocarcinoma ( 19836008) Rheumatoid arthritis ( 21844665)
Protein-Protein Interactions		16 interactors: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53	2 interactors: HGH1 KLF6
Entrez ID		1316	55937
HPRD ID		03632	06068
Ensembl ID		ENSG00000067082	ENSG00000204444
Uniprot IDs		D3GC14 Q99612	O95445
PDB IDs			2WEW 2WEX 2YG2
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Fluid Shear Stress Chromatin Organization Gene Expression Regulation Of RNA Metabolic Process Regulation Of DNA Replication Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Component Assembly RRNA Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Notch Signaling Pathway Protein Import Into Nucleus, Translocation Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Histone H3-K9 Modification Transcription, DNA-templated Response To Fluid Shear Stress RNA Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Chromatin Modification Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Growth Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Neuron Apoptotic Process Negative Regulation Of Signaling Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process
Tagcloud ?		allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic	a4 antitrypsin apoa apoc apod apof apoh apoj apol apolipoproteins atherogenic carry chd convincingly delipidation dense differs fibrinogen ldl lysosome originate paraoxonase prenylcysteine proteome sdldl strengthens subfractions transthyretin vldl
Tagcloud (Difference) ?		allowed anchorage arrest challenged constitutive conversion decreasing driven ectopic foci g12v highlighting hindering impaired jnk jun knockdown kruppel nih3t3 oncogenic p21 physiology ras relevance spontaneous stably transformed tumorigenesis tumorigenic	a4 antitrypsin apoa apoc apod apof apoh apoj apol apolipoproteins atherogenic carry chd convincingly delipidation dense differs fibrinogen ldl lysosome originate paraoxonase prenylcysteine proteome sdldl strengthens subfractions transthyretin vldl
Tagcloud (Intersection) ?