CASP8 and EIF2AK2

  • Number of citations of the paper that reports this interaction (PMID 11555640)
  • 30
  • Data Source:
  • HPRD (in vitro, in vivo)

CASP8

EIF2AK2

Gene Name caspase 8, apoptosis-related cysteine peptidase eukaryotic translation initiation factor 2-alpha kinase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM 48 interactors: CASP3 CASP7 CASP8 CDC42 CHUK DHX30 DHX58 DHX9 DICER1 DNAJC3 EDC4 EIF2S1 EIF6 ELF2 FTSJ3 HIST2H2AC HSP90AA1 HSPA1A IKBKB IL7R ILF2 ILF3 JAK1 MAP3K5 MAP3K7 METAP2 MOV10 NFKBIA NPM1 PDGFRB PPP1CA PPP1CC PPP2R5A PRKRA PRKRIP1 PRKRIR PTGES3 RAC1 STAT1 STAT3 STRBP TAB2 TARBP2 TIRAP TOLLIP TP53 TYK2 ZNF346
Entrez ID 841 5610
HPRD ID 03459 01468
Ensembl ID ENSG00000064012 ENSG00000055332
Uniprot IDs Q14790 B7ZKK7 P19525 Q8IW76
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 1QU6 2A19 2A1A 3UIU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
c1qdc1  cds1  crebbp  ctnnd1  cul1  customized  dner  eef2  fzd2  fzd9  g93a  gastrocnemius  id2  inppl1  keep  loxl2  neuromuscular  pi3  pik3c2a  pik4ca  piki3r1  precede  presymptomatic  prkx  rac3  ripk4  snf1lk  sod1  tbl1x 
Tagcloud (Difference) ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
c1qdc1  cds1  crebbp  ctnnd1  cul1  customized  dner  eef2  fzd2  fzd9  g93a  gastrocnemius  id2  inppl1  keep  loxl2  neuromuscular  pi3  pik3c2a  pik4ca  piki3r1  precede  presymptomatic  prkx  rac3  ripk4  snf1lk  sod1  tbl1x 
Tagcloud (Intersection) ?