CASP8 and PARP2

  • Number of citations of the paper that reports this interaction (PMID 12065591)
  • 7
  • Data Source:
  • HPRD (in vitro, in vivo)

CASP8

PARP2

Gene Name caspase 8, apoptosis-related cysteine peptidase poly (ADP-ribose) polymerase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM 6 interactors: BUB3 CASP8 CENPA CENPB PARP1 XRCC1
Entrez ID 841 10038
HPRD ID 03459 09660
Ensembl ID ENSG00000064012 ENSG00000129484
Uniprot IDs Q14790 Q9UGN5
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 3KCZ 3KJD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
abt  actively  adp  azd  bsi  continues  crystal  detailed  explored  guide  heightened  indications  inhibitors  insight  manifesting  modes  parp1  parp5a  parp5b  poly  rational  relevance  ribose  stranded  tankyrase  tnks1  tnks2  valuable 
Tagcloud (Difference) ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  phenolic  rosemary  sage  serves  sy5y 
abt  actively  adp  azd  bsi  continues  crystal  detailed  explored  guide  heightened  indications  inhibitors  insight  manifesting  modes  parp1  parp5a  parp5b  poly  rational  relevance  stranded  tankyrase  tnks1  tnks2  valuable 
Tagcloud (Intersection) ?
parp  ribose