CASP8 and CDKN1B

  • Number of citations of the paper that reports this interaction (PMID 11420686)
  • 6
  • Data Source:
  • HPRD (in vitro)

CASP8

CDKN1B

Gene Name caspase 8, apoptosis-related cysteine peptidase cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Systemic lupus erythematosus ( 23273568)
Protein-Protein Interactions 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM 62 interactors: ABL1 AKT1 ARHGDIA CAMK1 CASP8 CCNA1 CCNA2 CCNB1 CCND1 CCND2 CCND3 CCNE2 CDC34 CDK2 CDK3 CDK4 CDK5 CKS1B COPS5 CUL1 CUL4A GRB2 HIST1H1A HIST1H1B IRF1 KAT2B KPNA1 KPNA3 KPNA4 KPNA5 KPNA6 LYN MAPK10 MCM7 NUP50 PIN1 PSMB1 RCHY1 RNF123 RPS6KA1 SGK1 SKP1 SKP2 SPDYA SRC STMN1 TRAF2 TSC2 UBAC1 UBB UBE2B UBE2D2 UBE3A UCHL1 XPO1 YES1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 841 1027
HPRD ID 03459 02867
Ensembl ID ENSG00000064012 ENSG00000111276
Uniprot IDs Q14790 P46527 Q6I9V6
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7 1H27 1JSU 2AST
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
aggregated  anaplastic  atc  braf  cdkn2c  ctnnb1  eif1ax  exclusive  exome  harbored  hypermutator  landscape  mismatch  mlh  mlh1  mlh3  msh5  msh6  mutational  mutually  nf1  nf2  nras  ontology  pik3ca  ret  unresponsive  ush2a  v600e 
Tagcloud (Difference) ?
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
aggregated  anaplastic  atc  braf  cdkn2c  ctnnb1  eif1ax  exclusive  exome  harbored  hypermutator  landscape  mismatch  mlh  mlh1  mlh3  msh5  msh6  mutational  mutually  nf1  nf2  nras  ontology  pik3ca  ret  unresponsive  ush2a  v600e 
Tagcloud (Intersection) ?