NAP1L4 and BDKRB1

Number of citations: 90 (PubMedID 28298427)
Data Source: BioGRID (two hybrid)

		NAP1L4	BDKRB1
Name		nucleosome assembly protein 1 like 4	bradykinin receptor B1
Structure		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Dendrite Neuronal Cell Body	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding Unfolded Protein Binding	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Nucleosome Assembly	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		None	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		None	Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
GWAS		Aspartate aminotransferase levels ( 33547301 ) Calcium levels ( 20705733 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Malaria ( 31844061 ) Monocyte count ( 32888494 ) Neutrophil count ( 32888494 ) Platelet distribution width ( 32888494 ) White blood cell count ( 32888494 )	Metabolite levels ( 23823483 )
Novel Interactors		None recorded	2 novel interactors: DNAJB13 EVL
Interacting Genes		16 interacting genes: BDKRB1 CSNK2A1 CSNK2A2 EP300 ESR1 H1-1 H2AC20 H2AC8 H2BC21 H3-4 H3C14 H4C14 LINC01554 MTNR1A OGT UBC	32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		4676	623
HPRD ID		11873	02639
Ensembl ID		ENSG00000205531	ENSG00000100739
Uniprot IDs		Q99733	P46663
PDB IDs		Not available	7EIB
GO Terms Enriched among Interactors		Structural Constituent Of Chromatin Nucleosome Chromatin Organization Chromatin Remodeling Protein-DNA Complex Assembly Protein Localization To Chromosome Nucleosome Assembly Chromosome Nucleosome Organization Protein Localization To Chromatin Protein Heterodimerization Activity Protein Kinase CK2 Complex Rhythmic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process DNA Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Chromatin DNA Binding Protein-containing Complex Assembly Cellular Component Assembly Nucleoplasm CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Protein-containing Complex Organization Negative Regulation Of Macromolecule Metabolic Process Sin3-type Complex Negative Regulation Of Protein Catabolic Process Histone Acetyltransferase Complex Circadian Rhythm Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process PcG Protein Complex Negative Regulation Of Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Catabolic Process Nucleus Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Localization To Chromosome, Centromeric Region Transcription Coregulator Binding Negative Regulation Of Translational Initiation Regulation Of Proteasomal Protein Catabolic Process Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity	Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding