DOT1L and STAT1

  • Number of citations of the paper that reports this interaction (PMID 22002246)
  • 1
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

DOT1L

STAT1

Gene Name DOT1-like histone H3K79 methyltransferase signal transducer and activator of transcription 1, 91kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 4 interactors: HIST3H3 MLLT10 MLLT6 STAT1 103 interactors: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DOT1L DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 ERBB2 FADD FANCC FGFR3 FGFR4 FLT1 FOS FYN GFAP GNB2L1 GTF2I HADH HLA-B HSF1 HSP90AB1 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTBN1 SRC STAT2 STAT3 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBC UBE2I VDR XPO1 ZNF467
Entrez ID 84444 6772
HPRD ID 10455 02777
Ensembl ID ENSG00000104885 ENSG00000115415
Uniprot IDs Q8TEK3 J3KPM9 P42224
PDB IDs 1NW3 3QOW 3QOX 3SR4 3SX0 3UWP 4EK9 4EKG 4EKI 4EQZ 4ER0 4ER3 4ER5 4ER6 4ER7 4HRA 1BF5 1YVL 2KA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aberrant  balanced  blasts  catalyze  considerable  depending  deregulated  disturbed  drivers  histones  indirectly  leukemia  leukemic  lysine  marks  methylated  methyltransferases  mll1  oncogenic  originating  progenitor  recurrently  repressing  residue  setd2  tightly  transformed  translocations  writers 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
aberrant  balanced  blasts  catalyze  considerable  depending  deregulated  disturbed  drivers  histones  indirectly  leukemia  leukemic  lysine  marks  methylated  methyltransferases  mll1  oncogenic  originating  progenitor  recurrently  repressing  residue  setd2  tightly  transformed  translocations  writers 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Intersection) ?