CHAF1B and ZNF879

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		CHAF1B	ZNF879
Description		chromatin assembly factor 1 subunit B	zinc finger protein 879
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Nucleus
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		13 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A CUX1 H3-4 H3C6 PLEKHH1 RBBP4 SUMO2 ZNF879	1 interacting genes: CHAF1B
Entrez ID		8208	345462
HPRD ID		03147
Ensembl ID		ENSG00000159259	ENSG00000234284
Uniprot IDs		Q13112	B4DU55
PDB IDs		7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Chromatin Assembly Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly Cyclin-dependent Protein Kinase Activity CAF-1 Complex DNA Replication Histone Kinase Activity Protein-containing Complex Assembly Chromosome, Telomeric Region Protein-containing Complex Organization Histone Chaperone Activity Protein-containing Complex DNA Repair Cellular Component Assembly Cyclin-dependent Protein Serine/threonine Kinase Activity Cyclin Binding Response To Copper Ion Extracellular Exosome Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Prostaglandin E2 9-reductase Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity DNA Metabolic Process Pronuclear Fusion DNA Damage Response Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Histone Binding Chromatin Binding G2/M Transition Of Mitotic Cell Cycle Acetylcholine Receptor Activator Activity Regulation Of Transcription By RNA Polymerase II Lipoprotein Particle Positive Regulation Of Protein Import 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity S-nitrosoglutathione Reductase (NADPH) Activity Cell Cycle G2/M Phase Transition Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex	CAF-1 Complex DNA Replication-dependent Chromatin Assembly
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