CHAF1B and ASF1B

Number of citations of the paper that reports this interaction (PubMedID 11897662)
21

Data Source:
HPRD (in vivo)

		CHAF1B	ASF1B
Description		chromatin assembly factor 1 subunit B	anti-silencing function 1B histone chaperone
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Protein Binding Histone Binding Histone Chaperone Activity
	Biological Process	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response	Blastocyst Hatching Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		13 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A CUX1 H3-4 H3C6 PLEKHH1 RBBP4 SUMO2 ZNF879	13 interacting genes: ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4C16 H4C6 HCFC1 TAF1 TLK1 TLK2
Entrez ID		8208	55723
HPRD ID		03147	16460
Ensembl ID		ENSG00000159259	ENSG00000105011
Uniprot IDs		Q13112	Q9NVP2
PDB IDs		7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T	5BNX 5BO0 7V1M 7VCQ
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Chromatin Assembly Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly Cyclin-dependent Protein Kinase Activity CAF-1 Complex DNA Replication Histone Kinase Activity Protein-containing Complex Assembly Chromosome, Telomeric Region Protein-containing Complex Organization Histone Chaperone Activity Protein-containing Complex DNA Repair Cellular Component Assembly Cyclin-dependent Protein Serine/threonine Kinase Activity Cyclin Binding Response To Copper Ion Extracellular Exosome Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Prostaglandin E2 9-reductase Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity DNA Metabolic Process Pronuclear Fusion DNA Damage Response Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Histone Binding Chromatin Binding G2/M Transition Of Mitotic Cell Cycle Acetylcholine Receptor Activator Activity Regulation Of Transcription By RNA Polymerase II Lipoprotein Particle Positive Regulation Of Protein Import 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity S-nitrosoglutathione Reductase (NADPH) Activity Cell Cycle G2/M Phase Transition Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex	Nucleosome Assembly Protein-DNA Complex Assembly Chromatin Organization Nucleosome Organization Chromatin Remodeling Protein-containing Complex Structural Constituent Of Chromatin DNA Replication-dependent Chromatin Assembly Nucleosome Telomere Organization Protein-containing Complex Assembly Chromosome Organization Protein Heterodimerization Activity Protein-containing Complex Organization Nucleus Nucleoplasm CAF-1 Complex Chromosome Protein Localization To Chromatin Cellular Component Assembly DNA Damage Response Protein Localization To Chromosome CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Chromatin RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Chromatin Organization MLL1 Complex Chromosome, Telomeric Region Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome, Centromeric Region Chromatin Binding DNA Binding Positive Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Epigenetic Regulation Of Gene Expression Negative Regulation Of Protein Autoubiquitination Cadherin Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Phosphorylation Protein Serine Kinase Activity Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Chromosome Condensation Acetyl-CoA Binding Phosphorylation Muscle Cell Differentiation Pericentric Heterochromatin Formation Release From Viral Latency
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