TMOD3 and DUSP23

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TMOD3	DUSP23
Gene Name		tropomodulin 3 (ubiquitous)	dual specificity phosphatase 23
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Striated Muscle Thin Filament	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Tropomyosin Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Muscle Contraction Actin Filament Organization Myofibril Assembly Erythrocyte Development Pointed-end Actin Filament Capping Positive Regulation Of Mitotic Cell Cycle Phase Transition	Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS			C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Protein-Protein Interactions		4 interactors: CSNK2A1 DUSP23 MAP1LC3B TNFSF11	24 interactors: ASB13 CCDC186 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 KIAA1377 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746
Entrez ID		29766	54935
HPRD ID		10389	07908
Ensembl ID		ENSG00000138594	ENSG00000158716
Uniprot IDs		Q9NYL9	Q9BVJ7
PDB IDs			2IMG 4ERC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Corticotropin-releasing Hormone Secretion Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling TNFSF11-mediated Signaling Pathway Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Osteoclast Development Osteoclast Proliferation Regulation Of Osteoclast Development Positive Regulation Of Fever Generation Response To External Stimulus Regulation Of Fever Generation Positive Regulation Of Heat Generation Positive Regulation Of Prostaglandin Secretion Monocyte Chemotaxis Positive Regulation Of Bone Resorption Cellular Response To Nitrogen Starvation ERK1 And ERK2 Cascade Positive Regulation Of Icosanoid Secretion Nucleophagy Chemotaxis Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Fatty Acid Transport Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Acute Inflammatory Response Mitochondrion Degradation Positive Regulation Of Tissue Remodeling Regulation Of Fatty Acid Transport Regulation Of Bone Resorption Bone Resorption Tumor Necrosis Factor-mediated Signaling Pathway Organelle Disassembly Phosphate-containing Compound Metabolic Process Mitotic Spindle Checkpoint Activation Of JUN Kinase Activity Negative Regulation Of Chromosome Segregation Autophagic Vacuole Assembly Mammary Gland Lobule Development Regulation Of Bone Remodeling Mammary Gland Alveolus Development Osteoclast Differentiation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division	Cellular Metabolic Process Organelle Organization Regulation Of Gene Expression By Genetic Imprinting Gene Expression Genetic Imprinting Positive Regulation Of Histone Methylation Negative Regulation Of Male Germ Cell Proliferation Regulation Of Histone Methylation Positive Regulation Of Protein Modification Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process Regulation Of Male Germ Cell Proliferation Dihydrobiopterin Metabolic Process Cell Communication By Chemical Coupling S-adenosylmethioninamine Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization
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