DBI and PPCDC

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		DBI	PPCDC
Description		diazepam binding inhibitor, acyl-CoA binding protein	phosphopantothenoylcysteine decarboxylase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Protein-lipid Complex Extracellular Exosome Perinuclear Endoplasmic Reticulum	Cytosol Phosphopantothenoylcysteine Decarboxylase Complex
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding	Catalytic Activity Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding FMN Binding Lyase Activity Carboxy-lyase Activity Identical Protein Binding
	Biological Process	Fatty Acid Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Negative Regulation Of Protein Lipidation Positive Regulation Of Phospholipid Transport	Coenzyme A Biosynthetic Process
Pathways		Mitochondrial Fatty Acid Beta-Oxidation	Coenzyme A biosynthesis
Drugs		Coenzyme A Hexadecanal	Flavin mononucleotide Pantothenoylaminoethenethiol
Diseases
GWAS		Obesity-related traits ( 23251661)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Apolipoprotein A1 levels ( 32203549) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Coffee consumption (cups per day) ( 31837886) Heel bone mineral density ( 30598549) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Multisite chronic pain ( 33830993) Neutrophil count ( 32888494) Platelet count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 26502338) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: CYSLTR2 DDIT4L DUSP23 GSK3B LAMTOR5 MAP1LC3B NIPSNAP1 NSFL1C PFDN2 PPCDC RAD23A RAD23B TSPO UBXN2A	13 interacting genes: CENPT DBI DDIT4L FOXR1 NAA80 NTAQ1 PLEKHF2 PPIG PSMA1 SREK1IP1 TXN2 UBE2I ZNF232
Entrez ID		1622	60490
HPRD ID		08832	14377
Ensembl ID		ENSG00000155368	ENSG00000138621
Uniprot IDs		A0A024RAF2 B8ZWD1 B8ZWD8 P07108	H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2
PDB IDs		2CB8 2FJ9	1QZU
Enriched GO Terms of Interacting Partners?		Ubiquitin Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Protein Localization To Centrosome Proteasomal Protein Catabolic Process Autophagosome Assembly Autophagosome Organization Protein Catabolic Process Proteasome Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Organelle Assembly Nuclear Membrane Reassembly Regulation Of Proteolysis Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Catabolic Process Vacuole Organization Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Corticosterone Secretion Regulation Of Protein Metabolic Process Regulation Of Microtubule Anchoring At Centrosome Nuclear Membrane Organization Cysteinyl Leukotriene Receptor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Nucleotide-excision Repair Regulation Of Post-translational Protein Modification Macromolecule Catabolic Process Mitophagy Membrane Assembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Proteasome Complex Damaged DNA Binding Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Autophagy Of Mitochondrion VCP-NSFL1C Complex Negative Regulation Of Protein Localization To Centrosome Proteolysis Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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