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CEP70 and SERPINH1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CEP70
SERPINH1
Gene Name
centrosomal protein 70kDa
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Nuclear Membrane
Extracellular Space
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Serine-type Endopeptidase Inhibitor Activity
Collagen Binding
Poly(A) RNA Binding
Unfolded Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Chondrocyte Development Involved In Endochondral Bone Morphogenesis
Response To Unfolded Protein
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Organization
Collagen Fibril Organization
Collagen Biosynthetic Process
Protein Maturation
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
Collagen formation
Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS
Height (
20881960
22021425
)
Protein-Protein Interactions
134 interactors:
ABT1
AKAP17A
ARHGEF3
ATP5O
ATXN7
BARD1
BEX2
BRMS1
BYSL
C11orf57
C1orf35
C7orf25
C8orf33
CARD9
CCDC85B
CCDC94
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
DAZAP2
DDX41
DDX6
DIEXF
DNAJB11
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM214B
FAM64A
GATAD2B
GCC1
GPATCH2L
GPATCH4
GPX7
HAUS1
HMGB4
HSPD1
IK
IQCE
KANK2
KANSL1
KAT7
KDM1A
KRT31
LAMTOR5
LENG1
LENG8
LIN37
MCM10
MEST
METTL17
MFAP1
MRPL44
NIPSNAP3A
NKAP
NOL12
NOP2
NRIP1
NUSAP1
PAM16
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PRKRIP1
PRPF31
PSMA1
RCOR3
RPL13
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TCEB3
TCEB3B
TEAD4
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC25
TTLL10
TXLNB
UTP11L
UTP14A
ZBTB16
ZBTB24
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZGPAT
ZNF136
ZNF148
ZNF169
ZNF227
ZNF239
ZNF266
ZNF302
ZNF329
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF439
ZNF490
ZNF555
ZNF572
ZNF578
ZNF587
ZSCAN12
17 interactors:
BAG6
BRCA2
C1QL3
CD9
CDK9
CEP70
COL26A1
ESR2
FEZ1
HIST1H1B
HMP19
KLF13
PPARG
SLC2A4
SLC35F6
UBQLN4
UBTF
Entrez ID
80321
871
HPRD ID
16779
02968
Ensembl ID
ENSG00000114107
ENSG00000149257
Uniprot IDs
B7Z2D2
Q8NHQ1
A8K259
P50454
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
RRNA Processing
Regulation Of Cellular Process
RRNA Metabolic Process
Ribosomal Small Subunit Biogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
MRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone H3-K9 Dimethylation
RNA Processing
Chromatin Organization
Histone Modification
Maturation Of SSU-rRNA
Chromosome Organization
Cell Death
Death
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Apoptotic Process
Negative Regulation Of DNA Replication
DNA-templated Transcription, Initiation
Regulation Of Cell Proliferation
Negative Regulation Of DNA Metabolic Process
Negative Regulation Of Cell Proliferation
Regulation Of DNA Replication
Cell Maturation
Regulation Of Cellular Component Organization
Transcription Initiation From RNA Polymerase II Promoter
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Cellular Metabolic Process
Brown Fat Cell Differentiation
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Response To Metformin
Low-density Lipoprotein Particle Receptor Biosynthetic Process
Negative Regulation Of Pancreatic Stellate Cell Proliferation
Replication Fork Arrest
Response To Diuretic
Amylopectin Biosynthetic Process
Single Organism Reproductive Process
Regulation Of Cellular Process
Chromatin Organization
Regulation Of Cholesterol Transporter Activity
Cellular Response To Vitamin E
DNA-templated Transcription, Elongation
Reproductive Process
Apoptotic Signaling Pathway
Regulation Of Cell Growth
Brain Development
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Protein Stabilization
Macromolecule Biosynthetic Process
Head Development
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Multicellular Organism Reproduction
Steroid Hormone Mediated Signaling Pathway
Meiosis I
Membrane Organization
DNA-dependent DNA Replication
Cellular Response To Oxygen Levels
Transcription From RNA Polymerase II Promoter
Female Gonad Development
Regulation Of Gene Expression
Signal Transduction By P53 Class Mediator
Development Of Primary Female Sexual Characteristics
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Tagcloud
?
act
biochemical
bones
caused
chaperones
consequences
deficiency
destabilization
disorder
dominant
encode
fkbp10
forms
genes
genetic
growing
include
interact
little
maturation
mislocalization
moderately
mutant
mutation
posttranslational
predominantly
produce
reveal
secondarily
severe
Tagcloud (Difference)
?
act
biochemical
bones
caused
chaperones
consequences
deficiency
destabilization
disorder
dominant
encode
fkbp10
forms
genes
genetic
growing
include
interact
little
maturation
mislocalization
moderately
mutant
mutation
posttranslational
predominantly
produce
reveal
secondarily
severe
Tagcloud (Intersection)
?