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SERPINH1 and H1-5
Number of citations of the paper that reports this interaction (PubMedID
11581402
)
52
Data Source:
BioGRID
(pull down)
SERPINH1
H1-5
Description
serpin family H member 1
H1.5 linker histone, cluster member
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Extracellular Matrix
Membrane Raft
Chromatin
Nucleosome
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Molecular Function
RNA Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Collagen Binding
Unfolded Protein Binding
DNA Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
Structural Constituent Of Chromatin
Chromatin DNA Binding
Nucleosomal DNA Binding
Histone Deacetylase Binding
Biological Process
Chondrocyte Development Involved In Endochondral Bone Morphogenesis
Response To Unfolded Protein
Collagen Fibril Organization
Collagen Biosynthetic Process
Protein Maturation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Nucleosome Assembly
Muscle Organ Development
Chromosome Condensation
Negative Regulation Of DNA Recombination
Protein Stabilization
Establishment Of Protein Localization To Chromatin
Pathways
Collagen biosynthesis and modifying enzymes
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Coronary artery disease (
33020668
29212778
)
Height (
22021425
33713608
31562340
28552196
28270201
25429064
25282103
20881960
)
Hip circumference adjusted for BMI (
25673412
34021172
)
Myocardial infarction (
33532862
)
Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) (
28448500
)
Waist circumference adjusted for BMI in active individuals (
28448500
)
Waist circumference adjusted for body mass index (
28448500
34021172
)
Interacting Genes
20 interacting genes:
BAG6
BRCA2
C1QL3
CD9
CDK9
CEP70
COL26A1
ESR2
FEZ1
H1-5
KAT2B
KLF13
LINC01554
NSG2
OGT
PPARG
SLC2A4
SLC35F6
UBQLN4
UBTF
32 interacting genes:
CBX5
CCNA1
CCNA2
CCNB1
CCNE1
CDC42
CDK1
CDK2
CDK5
CDKN1A
CDKN1B
CEBPA
EHMT2
HPF1
IRAK4
KAT2A
KAT2B
L3MBTL1
LOX
MELK
MLLT1
NSD1
PARP1
PARP2
PRKCA
PRKCB
PRKCD
PRKCZ
RIPK3
RPS6KA5
SERPINH1
SIRT1
Entrez ID
871
3009
HPRD ID
02968
00821
Ensembl ID
ENSG00000149257
ENSG00000184357
Uniprot IDs
A8K259
P50454
P16401
PDB IDs
2RHI
Enriched GO Terms of Interacting Partners
?
Gamma-tubulin Binding
Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Positive Regulation Of Transcription By Glucose
Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Carbon Catabolite Regulation Of Transcription
Histone H3 Acetyltransferase Activity
Internal Peptidyl-lysine Acetylation
Response To Insulin
Regulation Of Transcription By Glucose
Internal Protein Amino Acid Acetylation
Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Component Organization
Cellular Response To Insulin Stimulus
Regulation Of Cellular Response To Stress
Chromatin Organization
Regulation Of Cellular Component Organization
Regulation Of Organelle Organization
Histone Acetyltransferase Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Response To Peptide Hormone
Histone Acetyltransferase Activity
Cellular Response To Low-density Lipoprotein Particle Stimulus
Positive Regulation Of Lipid Metabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Metabolic Process
Response To Nutrient
Protein Acetylation
Replication Fork Processing
BRCA2-MAGE-D1 Complex
Positive Regulation Of RNA Metabolic Process
Cellular Response To Lipoprotein Particle Stimulus
Host-mediated Activation Of Viral Process
Pyruvate Carboxylase Activity
Positive Regulation Of Fatty Acid Metabolic Process
Amylopectin Biosynthetic Process
D-glucose Uniporter Activity
Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
Polyubiquitin Modification-dependent Protein Binding
Negative Regulation Of Catabolic Process
Protein N-acetylglucosaminyltransferase Complex
Negative Regulation Of Non-canonical Inflammasome Complex Assembly
Cellular Response To Nutrient
Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion
Negative Regulation Of Macroautophagy
Collagen Type XXVI Trimer
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Peptide Hormone Stimulus
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Chromatin Remodeling
Protein Modification Process
Cell Cycle G1/S Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Chromatin Organization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Protein Serine Kinase Activity
Chromatin Binding
Protein Serine/threonine Kinase Activity
Transferase Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
Cyclin-dependent Protein Kinase Holoenzyme Complex
Regulation Of RNA Metabolic Process
Kinase Activity
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Nucleoplasm
Regulation Of DNA Metabolic Process
Protein Kinase Activity
Regulation Of Cell Cycle
Cellular Response To Oxygen-containing Compound
Cellular Response To Stress
Regulation Of Gene Expression
Regulation Of Cell Cycle Process
Regulation Of Macromolecule Biosynthetic Process
Response To Stress
Nucleus
Protein Kinase Binding
Cyclin A2-CDK2 Complex
Negative Regulation Of Macromolecule Biosynthetic Process
Protein Phosphorylation
Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cell Cycle
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
Intracellular Signal Transduction
Phosphorylation
Diacylglycerol-dependent Serine/threonine Kinase Activity
Protein Kinase C Signaling
Positive Regulation Of DNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cellular Component Organization
Negative Regulation Of RNA Metabolic Process
Cell Cycle G2/M Phase Transition
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Tagcloud (Difference)
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Tagcloud (Intersection)
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