CEP70 and ZNF417

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		CEP70	ZNF417
Description		centrosomal protein 70	zinc finger protein 417
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding Gamma-tubulin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Generic Transcription Pathway
Drugs
Diseases
GWAS		Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Femur bone mineral density x serum urate levels interaction ( 34046847) Male-pattern baldness ( 28196072)	Depression in smokers ( 30219690)
Interacting Genes		245 interacting genes: ABT1 AGBL2 AKAP17A ARHGEF3 ARMCX1 ATOSB ATP5PO ATXN7 BARD1 BAZ2B BEX2 BRD1 BRMS1 BRMS1L BRPF1 BYSL C1orf35 C7orf25 C8orf33 CARD9 CAVIN3 CBX8 CCDC187 CCDC85B CDC37 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL CWF19L2 DAXX DAZAP2 DDX41 DDX6 DNAJB11 DNTTIP2 DRC4 DVL3 DYRK1A EAF1 EBNA1BP2 EIF3D ELOA ELOA2 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM161B FAM90A1 GADD45GIP1 GATAD2B GCC1 GEM GLYCTK GPATCH2L GPATCH4 GPX7 GSE1 HAUS1 HDAC4 HDAC6 HIC2 HMGB4 HOXB5 HOXC8 HSPD1 IK INO80B INPP5J IPCEF1 IQCE IQUB ITPKB KANK2 KANSL1 KAT14 KAT5 KAT7 KDM1A KRI1 KRT31 LAMTOR5 LCOR LENG1 LENG8 LIN37 LNX1 MAB21L2 MAGOH MBD3 MCM10 MCRS1 MEST METTL17 MFAP1 MKRN3 MRPL44 NEBL NIPSNAP3A NKAP NKAPD1 NOL12 NOP2 NOP53 NOXA1 NRIP1 NTAQ1 NUSAP1 ODAD4 PAM16 PIBF1 PIMREG PKN1 PLA2G2A PPFIA1 PPIG PPP1R16B PPP1R18 PRKRIP1 PRPF18 PRPF3 PRPF31 PSMA1 PSORS1C2 RASSF10 RBM10 RCOR3 RHPN1 RNF169 RNF6 RPL13 SCNM1 SEC14L1 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SNW1 SOD2 SPANXN3 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TBC1D22B TBC1D30 TCAF1 TCEA2 TCEANC TEAD4 TLK2 TRAF3IP3 TRIM29 TRIM3 TRIM42 TSFM TSGA10IP TSHZ3 TTLL10 TXLNB TXN2 USP2 UTP11 UTP14A UTP14C UTP25 UTP3 VXN WT1 YJU2 ZBTB16 ZBTB24 ZBTB4 ZBTB47 ZBTB48 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZFHX3 ZFP1 ZFP91 ZGPAT ZNF136 ZNF140 ZNF148 ZNF165 ZNF169 ZNF17 ZNF20 ZNF202 ZNF227 ZNF239 ZNF250 ZNF264 ZNF266 ZNF302 ZNF329 ZNF35 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF433 ZNF439 ZNF490 ZNF491 ZNF555 ZNF557 ZNF572 ZNF574 ZNF578 ZNF587 ZNF599 ZNF607 ZNF648 ZNF669 ZNF688 ZNF696 ZNF775 ZNF777 ZNF785 ZNF835 ZNF860 ZSCAN12 ZSCAN21 ZSCAN23	170 interacting genes: - ADAMTSL4 AXIN2 BEGAIN BEND5 BEX3 BICD2 C4orf17 CARD9 CBY2 CCDC125 CCDC136 CCDC57 CCDC85B CCNDBP1 CDR2 CDR2L CEP44 CEP70 CEP72 CEP85L CHRDL2 COG6 CSRNP1 CYSRT1 DEF8 DVL3 EFS EZHIP FAM221A FHL2 FHL3 FHL5 FRS3 FSD2 FXR1 GOLGA2 GOLGA6L9 GPRASP3 HMBOX1 HOMEZ HOOK2 HOXA1 HSF2BP IGFBP6 IHO1 IKZF1 INKA1 JADE2 JRK KAT5 KATNBL1 KCTD7 KIF9 KIFC3 KLC3 KRT15 KRT31 KRT35 KRT38 KRT39 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-9 KXD1 LHX3 LIMS1 LMO1 LURAP1 LZTS1 LZTS2 MAGEA8 MAST2 MCC MCCD1 MDFI MEIS3 MEOX2 MID2 MIIP MRFAP1L1 MTUS2 MYF5 MYLIP NAB2 NBPF19 NDEL1 NDUFB7 NINL NKAPL NKX3-1 NOTCH2NLA OIP5 PHC2 PICK1 PIH1D2 PLSCR1 PNMA2 PRICKLE4 PRPF31 RCN3 REL RHOQ RNF187 RORB RPGRIP1 RUNDC3A SH2B2 SMARCD1 SMYD5 SPRED1 SPRED2 SPRY1 SPRY2 SSX2IP STX11 SUV39H1 TADA2A TCF4 TEKT4 TFIP11 TLE5 TMCC2 TNS2 TRAF1 TRAF2 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXNDC11 U2AF1 USHBP1 VPS16 VPS52 VWC2 ZBTB1 ZBTB10 ZBTB43 ZBTB8A ZBTB9 ZNF165 ZNF19 ZNF20 ZNF547 ZNF572 ZNF587 ZNF69 ZNF71 ZNF768 ZNF774 ZNF837 ZNF85 ZRANB1
Entrez ID		80321	147687
HPRD ID		16779	18341
Ensembl ID		ENSG00000114107	ENSG00000173480
Uniprot IDs		A0A140VJG2 B7Z2D2 Q8NHQ1	M0R230 Q8TAU3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Nucleus Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleolus RNA Processing Nuclear Speck Spliceosomal Complex Nucleoplasm RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone Acetyltransferase Complex Chromatin Organization Nuclear Androgen Receptor Binding Protein-RNA Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Chromosome Transcription Elongation By RNA Polymerase II RRNA Processing RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Remodeling Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process RNA Binding DNA-templated Transcription Elongation RNA Metabolic Process Histone H3-K14 Acetyltransferase Complex MRNA Processing Ribonucleoprotein Complex Biogenesis RRNA Metabolic Process Nucleic Acid Metabolic Process	Keratin Filament Intermediate Filament Protein Binding Identical Protein Binding Zinc Ion Binding Negative Regulation Of Lens Fiber Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Structural Constituent Of Skin Epidermis Cytoskeleton Protein Serine/threonine Kinase Inhibitor Activity Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Microtubule Binding Cytoskeleton Organization Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Microtubule DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Organelle Organization Hair Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Stem Cell Factor Receptor Binding
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