SERPINH1 and COL26A1

Number of citations of the paper that reports this interaction (PubMedID 12145293)
0

Data Source:
HPRD (two hybrid)

		SERPINH1	COL26A1
Description		serpin family H member 1	collagen type XXVI alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Matrix Membrane Raft	Extracellular Region Collagen Trimer Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Extracellular Matrix Collagen Type XXVI Trimer
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Positive Regulation Of Cell-substrate Adhesion
Pathways		Collagen biosynthesis and modifying enzymes	Collagen degradation Collagen biosynthesis and modifying enzymes Collagen chain trimerization
Drugs
Diseases
GWAS		A body shape index ( 34021172) Coronary artery disease ( 33020668 29212778) Height ( 22021425 33713608 31562340 28552196 28270201 25429064 25282103 20881960) Hip circumference adjusted for BMI ( 25673412 34021172) Myocardial infarction ( 33532862) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500 34021172)	Diffusing capacity of carbon monoxide ( 30694715) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Lysophosphatidylcholine levels ( 31551469)
Interacting Genes		20 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KAT2B KLF13 LINC01554 NSG2 OGT PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	3 interacting genes: EMID1 SERPINH1 TBP
Entrez ID		871	136227
HPRD ID		02968	16405
Ensembl ID		ENSG00000149257	ENSG00000160963
Uniprot IDs		A8K259 P50454	Q96A83
PDB IDs			4AU2 4AU3 4BJ3 7BDU 7BEE 7BFI
Enriched GO Terms of Interacting Partners?		Gamma-tubulin Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbon Catabolite Regulation Of Transcription Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Response To Insulin Regulation Of Transcription By Glucose Internal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Negative Regulation Of Cellular Component Organization Cellular Response To Insulin Stimulus Regulation Of Cellular Response To Stress Chromatin Organization Regulation Of Cellular Component Organization Regulation Of Organelle Organization Histone Acetyltransferase Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Response To Peptide Hormone Histone Acetyltransferase Activity Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Lipid Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Metabolic Process Response To Nutrient Protein Acetylation Replication Fork Processing BRCA2-MAGE-D1 Complex Positive Regulation Of RNA Metabolic Process Cellular Response To Lipoprotein Particle Stimulus Host-mediated Activation Of Viral Process Pyruvate Carboxylase Activity Positive Regulation Of Fatty Acid Metabolic Process Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Nutrient Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Negative Regulation Of Macroautophagy Collagen Type XXVI Trimer Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Extracellular Matrix Chondrocyte Development Involved In Endochondral Bone Morphogenesis RNA Polymerase Transcription Factor SL1 Complex TFIIB-class Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Binding Male Pronucleus Transcription Factor TFIIA Complex Aryl Hydrocarbon Receptor Binding Pronucleus RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Female Pronucleus Collagen Biosynthetic Process RNA Polymerase III General Transcription Initiation Factor Activity Female Germ Cell Nucleus Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Chondrocyte Development Transcription Factor TFIID Complex Transcription By RNA Polymerase III RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Transcription Initiation At RNA Polymerase II Promoter Male Germ Cell Nucleus Collagen Metabolic Process Collagen Fibril Organization Collagen Binding MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Euchromatin Positive Regulation Of DNA-templated Transcription Initiation DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Collagen Trimer Response To Unfolded Protein Serine-type Endopeptidase Inhibitor Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Regulation Of DNA-templated Transcription Initiation
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