CEP70 and C1orf35

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid)

		CEP70	C1orf35
Gene Name		centrosomal protein 70kDa	chromosome 1 open reading frame 35
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12	9 interactors: APP CEP70 DACH1 FXR2 GOLGA2 SDCBP2 SRPK2 TERF1 THAP1
Entrez ID		80321	79169
HPRD ID		16779	10090
Ensembl ID		ENSG00000114107	ENSG00000143793
Uniprot IDs		B7Z2D2 Q8NHQ1	Q9BU76
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process	Suckling Behavior Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Nuclear Speck Organization Regulation Of Mitotic Cell Cycle Feeding Behavior Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Cycle Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Protein Binding Telomere Maintenance Via Telomere Shortening Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Telomere Maintenance Via Telomerase Mitotic Cell Cycle Axon Choice Point Recognition Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Negative Regulation Of Transcription By Competitive Promoter Binding Neuron Remodeling Replicative Cell Aging Cellular Component Assembly Negative Regulation Of Protein Metabolic Process Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Binding Mitotic Cell Cycle Phase Transition Contact Inhibition Regulation Of Telomere Maintenance Via Telomerase Cell Cycle Phase Transition Regulation Of Translation Positive Regulation Of Microtubule Polymerization Negative Regulation Of Cellular Metabolic Process Regulation Of Telomerase Activity Endothelial Cell Proliferation Cellular Copper Ion Homeostasis Negative Regulation Of Proteolysis Regulation Of Telomere Maintenance
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