SERPINH1 and NSG2

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		SERPINH1	NSG2
Name		serpin family H member 1	neuronal vesicle trafficking associated 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Matrix Membrane Raft	Lysosome Endosome Early Endosome Late Endosome Golgi Apparatus Endosome Membrane Membrane Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Cell Projection Lysosomal Lumen Postsynaptic Density Membrane Glutamatergic Synapse Golgi Cis Cisterna Membrane
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding	Protein Binding Clathrin Light Chain Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Endosomal Transport Clathrin Coat Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Pathways		Collagen biosynthesis and modifying enzymes	None
GWAS		A body shape index ( 34021172 ) Coronary artery disease ( 33020668 29212778 ) Height ( 22021425 33713608 31562340 28552196 28270201 25429064 25282103 20881960 ) Hip circumference adjusted for BMI ( 25673412 34021172 ) Myocardial infarction ( 33532862 ) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500 ) Waist circumference adjusted for BMI in active individuals ( 28448500 ) Waist circumference adjusted for body mass index ( 28448500 34021172 )	Alzheimer's disease ( 33074286 ) Blond vs. brown/black hair color ( 30531825 ) Diffusing capacity of carbon monoxide ( 30694715 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Novel Interactors		1 novel interactors: PC	None recorded
Interacting Genes		20 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KAT2B KLF13 LINC01554 NSG2 OGT PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768
Entrez ID		871	51617
HPRD ID		02968	13664
Ensembl ID		ENSG00000149257	ENSG00000170091
Uniprot IDs		A8K259 P50454	Q9Y328
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Gamma-tubulin Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbon Catabolite Regulation Of Transcription Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Response To Insulin Regulation Of Transcription By Glucose Internal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Negative Regulation Of Cellular Component Organization Cellular Response To Insulin Stimulus Regulation Of Cellular Response To Stress Chromatin Organization Regulation Of Cellular Component Organization Regulation Of Organelle Organization Histone Acetyltransferase Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Response To Peptide Hormone Histone Acetyltransferase Activity Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Lipid Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Metabolic Process Response To Nutrient Protein Acetylation Replication Fork Processing BRCA2-MAGE-D1 Complex Positive Regulation Of RNA Metabolic Process Cellular Response To Lipoprotein Particle Stimulus Host-mediated Activation Of Viral Process Pyruvate Carboxylase Activity Positive Regulation Of Fatty Acid Metabolic Process Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Nutrient Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Negative Regulation Of Macroautophagy Collagen Type XXVI Trimer Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	None