CEP70 and METTL17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP70	METTL17
Gene Name		centrosomal protein 70kDa	methyltransferase like 17
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane	Nucleus Nucleoplasm Mitochondrion Ribosome
	Molecular Function	Protein Binding	Copper Ion Binding Protein Binding Methyltransferase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Translation Methylation
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12	14 interactors: ATXN1 ATXN1L CALCOCO2 CEP70 KRT40 MAPK6 MDFI MID2 PNMA1 SF3B4 SPERT TFIP11 TRAF1 TRIP6
Entrez ID		80321	64745
HPRD ID		16779	13379
Ensembl ID		ENSG00000114107	ENSG00000165792
Uniprot IDs		B7Z2D2 Q8NHQ1	Q9H7H0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process	Lung Alveolus Development Regulation Of RNA Metabolic Process Spliceosomal Complex Disassembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Release Of Cytoplasmic Sequestered NF-kappaB RNA Processing Negative Regulation Of Gene Expression Regulation Of Protein Import Into Nucleus Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Localization To Microtubule Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity MAPK Cascade MRNA Splicing, Via Spliceosome Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Splicing, Via Transesterification Reactions Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Signal Transduction Lung Development Respiratory Tube Development Regulation Of Intracellular Protein Transport Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Signal Transduction By Phosphorylation Negative Regulation Of Viral Entry Into Host Cell Respiratory System Development Trophoblast Giant Cell Differentiation
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