CEP70 and STMN2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CEP70	STMN2
Gene Name		centrosomal protein 70kDa	stathmin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane	Cytoplasm Endosome Golgi Apparatus Membrane Lamellipodium Axon Growth Cone Vesicle Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization	Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Cellular Response To Nerve Growth Factor Stimulus
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Creutzfeldt-Jakob disease ( 19081515)
Protein-Protein Interactions		134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12	17 interactors: CCDC85A CDK1 CEP70 EEF1A1 GPRASP1 GPRASP2 MAPK10 MAPK3 NGFR PRKACA RGS20 RGS6 SUMO1 TEX11 TFCP2 TRPC5 TXLNA
Entrez ID		80321	11075
HPRD ID		16779	09003
Ensembl ID		ENSG00000114107	ENSG00000104435
Uniprot IDs		B7Z2D2 Q8NHQ1	E5RGX5 Q93045
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Nuclear Envelope Organization Neurotrophin Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Activation Of Protein Kinase Activity Regulation Of Signaling Response To Growth Factor Chemotaxis Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Nucleus Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Axon Guidance Activation Of MAPK Activity Activation Of Innate Immune Response Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Epidermal Growth Factor Positive Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Mitotic Nuclear Envelope Disassembly Axonogenesis Positive Regulation Of MAP Kinase Activity
Tagcloud ?			bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Difference) ?			bcl11a cpg f9 gab1 h3k4me3 h3k9 h3k9me3 hmgcs1 imprinting island k14ac knockout mest mobp modifications permissive rara raralpha rars recapitulated ref2l repressive rlf1 rpl39l rxralpha slc38a4 tcfap2a tex13 transcript
Tagcloud (Intersection) ?