SERPINH1 and C1QL3

Number of citations: 0 (PubMedID 10862616)
Data Source: HPRD (two hybrid, in vitro)

		SERPINH1	C1QL3
Name		serpin family H member 1	complement C1q like 3
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Matrix Membrane Raft	Extracellular Region Collagen Trimer Synaptic Cleft Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Collagen Binding Unfolded Protein Binding	Identical Protein Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Regulation Of Synapse Organization Postsynaptic Density Assembly Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Pathways		Collagen biosynthesis and modifying enzymes	None
GWAS		A body shape index ( 34021172 ) Coronary artery disease ( 33020668 29212778 ) Height ( 22021425 33713608 31562340 28552196 28270201 25429064 25282103 20881960 ) Hip circumference adjusted for BMI ( 25673412 34021172 ) Myocardial infarction ( 33532862 ) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500 ) Waist circumference adjusted for BMI in active individuals ( 28448500 ) Waist circumference adjusted for body mass index ( 28448500 34021172 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: PC	None recorded
Interacting Genes		20 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KAT2B KLF13 LINC01554 NSG2 OGT PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	2 interacting genes: ADGRB3 SERPINH1
Entrez ID		871	389941
HPRD ID		02968	16632
Ensembl ID		ENSG00000149257	ENSG00000165985
Uniprot IDs		A8K259 P50454	A0A3B0J0F3 Q5VWW1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Gamma-tubulin Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbon Catabolite Regulation Of Transcription Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Response To Insulin Regulation Of Transcription By Glucose Internal Protein Amino Acid Acetylation Peptidyl-lysine Acetylation Negative Regulation Of Cellular Component Organization Cellular Response To Insulin Stimulus Regulation Of Cellular Response To Stress Chromatin Organization Regulation Of Cellular Component Organization Regulation Of Organelle Organization Histone Acetyltransferase Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Response To Peptide Hormone Histone Acetyltransferase Activity Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Lipid Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Metabolic Process Response To Nutrient Protein Acetylation Replication Fork Processing BRCA2-MAGE-D1 Complex Positive Regulation Of RNA Metabolic Process Cellular Response To Lipoprotein Particle Stimulus Host-mediated Activation Of Viral Process Pyruvate Carboxylase Activity Positive Regulation Of Fatty Acid Metabolic Process Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Nutrient Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Negative Regulation Of Macroautophagy Collagen Type XXVI Trimer Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Regulation Of Synapse Pruning Neuron Remodeling Motor Learning Cerebellar Climbing Fiber To Purkinje Cell Synapse Collagen Biosynthetic Process Chondrocyte Development Involved In Endochondral Bone Morphogenesis Myoblast Fusion Maintenance Of Synapse Structure Neuron Maturation Synaptic Cleft Regulation Of Synapse Maturation Chondrocyte Development Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Cellular Component Maintenance Cell Junction Maintenance Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Collagen Metabolic Process Collagen Fibril Organization Collagen Binding Response To Unfolded Protein Serine-type Endopeptidase Inhibitor Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Regulation Of Dendrite Development Postsynaptic Density Membrane Positive Regulation Of Cell Junction Assembly Unfolded Protein Binding