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CEP70 and SRGN
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
CEP70
SRGN
Gene Name
centrosomal protein 70kDa
serglycin
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Nuclear Membrane
Golgi Membrane
Extracellular Region
Extracellular Space
Golgi Apparatus
Platelet Alpha Granule Lumen
Zymogen Granule
Mast Cell Granule
Molecular Function
Protein Binding
Protein Binding
Collagen Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Platelet Degranulation
Blood Coagulation
Granzyme-mediated Apoptotic Signaling Pathway
Protein Processing
Platelet Activation
Negative Regulation Of Bone Mineralization
Biomineral Tissue Development
Mast Cell Secretory Granule Organization
T Cell Secretory Granule Organization
Maintenance Of Protease Location In Mast Cell Secretory Granule
Maintenance Of Granzyme B Location In T Cell Secretory Granule
Negative Regulation Of Cytokine Secretion
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
Response to elevated platelet cytosolic Ca2+
Platelet degranulation
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions
134 interactors:
ABT1
AKAP17A
ARHGEF3
ATP5O
ATXN7
BARD1
BEX2
BRMS1
BYSL
C11orf57
C1orf35
C7orf25
C8orf33
CARD9
CCDC85B
CCDC94
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
DAZAP2
DDX41
DDX6
DIEXF
DNAJB11
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM214B
FAM64A
GATAD2B
GCC1
GPATCH2L
GPATCH4
GPX7
HAUS1
HMGB4
HSPD1
IK
IQCE
KANK2
KANSL1
KAT7
KDM1A
KRT31
LAMTOR5
LENG1
LENG8
LIN37
MCM10
MEST
METTL17
MFAP1
MRPL44
NIPSNAP3A
NKAP
NOL12
NOP2
NRIP1
NUSAP1
PAM16
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PRKRIP1
PRPF31
PSMA1
RCOR3
RPL13
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TCEB3
TCEB3B
TEAD4
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC25
TTLL10
TXLNB
UTP11L
UTP14A
ZBTB16
ZBTB24
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZGPAT
ZNF136
ZNF148
ZNF169
ZNF227
ZNF239
ZNF266
ZNF302
ZNF329
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF439
ZNF490
ZNF555
ZNF572
ZNF578
ZNF587
ZSCAN12
12 interactors:
ALB
BAG6
CCL3
CD44
CEP70
GZMB
PF4
PSRC1
SGTA
UBQLN1
UBQLN4
UBR4
Entrez ID
80321
5552
HPRD ID
16779
01513
Ensembl ID
ENSG00000114107
ENSG00000122862
Uniprot IDs
B7Z2D2
Q8NHQ1
P10124
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
RRNA Processing
Regulation Of Cellular Process
RRNA Metabolic Process
Ribosomal Small Subunit Biogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
MRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone H3-K9 Dimethylation
RNA Processing
Chromatin Organization
Histone Modification
Maturation Of SSU-rRNA
Chromosome Organization
Cell Death
Death
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Apoptotic Process
Regulation Of Apoptotic Process
Regulation Of Cell Death
Positive Regulation Of Behavior
Cytolysis
Regulation Of Behavior
Leukocyte Migration
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Leukocyte Chemotaxis
Exocytosis
Platelet Degranulation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Monocyte Aggregation
Maintenance Of Mitochondrion Location
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Cell Death
Blood Coagulation
Inflammatory Response
Hemostasis
Leukocyte Chemotaxis
Positive Regulation Of Chemotaxis
Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Leukocyte Migration
Monocyte Aggregation
Response To Platinum Ion
Negative Regulation Of Cytolysis
Hemolysis By Symbiont Of Host Erythrocytes
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Eosinophil Degranulation
Regulation Of Cellular Protein Metabolic Process
Secretion By Cell
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Chemotaxis
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Natural Killer Cell Chemotaxis
Granzyme-mediated Apoptotic Signaling Pathway
Cellular Response To Interferon-gamma
Regulation Of Body Fluid Levels
Cellular Response To Cytokine Stimulus
Positive Regulation Of Signal Transduction
Regulation Of Intrinsic Apoptotic Signaling Pathway
Immune System Process
Response To Endoplasmic Reticulum Stress
Regulation Of Protein Metabolic Process
Negative Regulation Of MHC Class II Biosynthetic Process
Wound Healing
Immune Response
Tagcloud
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
trem2
tubal3
txnrd1
Tagcloud (Difference)
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
trem2
tubal3
txnrd1
Tagcloud (Intersection)
?