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CEP70 and HSPD1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CEP70
HSPD1
Gene Name
centrosomal protein 70kDa
heat shock 60kDa protein 1 (chaperonin)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Nuclear Membrane
Extracellular Space
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Early Endosome
Cytosol
Plasma Membrane
Coated Pit
Cell Surface
Membrane
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
Coated Vesicle
Secretory Granule
Protein Complex
Lipopolysaccharide Receptor Complex
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Lipopolysaccharide Binding
P53 Binding
DNA Replication Origin Binding
Single-stranded DNA Binding
Double-stranded RNA Binding
Protein Binding
ATP Binding
ATPase Activity
Ubiquitin Protein Ligase Binding
Poly(A) RNA Binding
Unfolded Protein Binding
Chaperone Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
B Cell Cytokine Production
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
'de Novo' Protein Folding
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Unfolded Protein
Viral Process
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Protein Refolding
B Cell Proliferation
T Cell Activation
B Cell Activation
Positive Regulation Of Macrophage Activation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Isotype Switching To IgG Isotypes
Protein Stabilization
Positive Regulation Of T Cell Activation
Chaperone-mediated Protein Complex Assembly
Protein Maturation
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions
134 interactors:
ABT1
AKAP17A
ARHGEF3
ATP5O
ATXN7
BARD1
BEX2
BRMS1
BYSL
C11orf57
C1orf35
C7orf25
C8orf33
CARD9
CCDC85B
CCDC94
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
DAZAP2
DDX41
DDX6
DIEXF
DNAJB11
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM214B
FAM64A
GATAD2B
GCC1
GPATCH2L
GPATCH4
GPX7
HAUS1
HMGB4
HSPD1
IK
IQCE
KANK2
KANSL1
KAT7
KDM1A
KRT31
LAMTOR5
LENG1
LENG8
LIN37
MCM10
MEST
METTL17
MFAP1
MRPL44
NIPSNAP3A
NKAP
NOL12
NOP2
NRIP1
NUSAP1
PAM16
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PRKRIP1
PRPF31
PSMA1
RCOR3
RPL13
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TCEB3
TCEB3B
TEAD4
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC25
TTLL10
TXLNB
UTP11L
UTP14A
ZBTB16
ZBTB24
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZGPAT
ZNF136
ZNF148
ZNF169
ZNF227
ZNF239
ZNF266
ZNF302
ZNF329
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF439
ZNF490
ZNF555
ZNF572
ZNF578
ZNF587
ZSCAN12
40 interactors:
ALDH2
APP
BAK1
BRCA1
CA2
CASP3
CASP9
CEP70
CLEC7A
CLU
DHFR
ERG
FHIT
HIST2H2BE
HSPE1
ITGA3
ITGB1
KRT31
KRT40
KRTAP10-3
KRTAP10-8
KRTAP5-9
LRRK2
LZTS2
MAPK6
NOTCH2NL
NR3C1
PLG
PPP2R1A
PPP2R1B
PRKACA
PRNP
RASA1
RGS20
SAMD3
SIRT3
SUMO4
TLR1
TMCC2
YWHAG
Entrez ID
80321
3329
HPRD ID
16779
00318
Ensembl ID
ENSG00000114107
ENSG00000144381
Uniprot IDs
B7Z2D2
Q8NHQ1
P10809
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
RRNA Processing
Regulation Of Cellular Process
RRNA Metabolic Process
Ribosomal Small Subunit Biogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
MRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone H3-K9 Dimethylation
RNA Processing
Chromatin Organization
Histone Modification
Maturation Of SSU-rRNA
Chromosome Organization
Cell Death
Death
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Cell Death
Cell Death
Regulation Of Cell Death
Death
Apoptotic Process
Positive Regulation Of Apoptotic Process
Programmed Cell Death
Developmental Process
Response To Organic Substance
Negative Regulation Of Signal Transduction
Negative Regulation Of Protein Metabolic Process
Apoptotic Signaling Pathway
Response To Stimulus
Negative Regulation Of Signaling
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Protein Metabolic Process
Signaling
Negative Regulation Of Cellular Protein Metabolic Process
Cell Communication
Signal Transduction
Positive Regulation Of Proteolysis
Regulation Of Cellular Protein Metabolic Process
Regulation Of Signaling
Negative Regulation Of Protein Phosphorylation
Regulation Of Proteolysis
Regulation Of Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Protein Metabolic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Intracellular Signal Transduction
Cell Differentiation
Cell Cycle Process
Negative Regulation Of Phosphorylation
Response To Stress
Mitotic Cell Cycle Phase Transition
Regulation Of Protein Phosphorylation
Cell Cycle Phase Transition
Cell Cycle
Anatomical Structure Development
Regulation Of Cell Adhesion
Positive Regulation Of Peptidase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Response To Radiation
Anatomical Structure Morphogenesis
Positive Regulation Of Neuron Death
Regulation Of Neuron Death
Response To Organic Cyclic Compound
Tagcloud
?
5d
achieved
complicated
contributed
dimerization
earliest
endogenous
enhanced
facilitated
heat
hsp60
ifn
ikkepsilon
induction
interacted
interacting
interferon
irf3
knockdown
mavs
mda
mock
phosphorylated
progress
protective
rig
sev
shock
tbk1
Tagcloud (Difference)
?
5d
achieved
complicated
contributed
dimerization
earliest
endogenous
enhanced
facilitated
heat
hsp60
ifn
ikkepsilon
induction
interacted
interacting
interferon
irf3
knockdown
mavs
mda
mock
phosphorylated
progress
protective
rig
sev
shock
tbk1
Tagcloud (Intersection)
?