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CEP70 and ERCC3
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CEP70
ERCC3
Gene Name
centrosomal protein 70kDa
excision repair cross-complementation group 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Nuclear Membrane
Core TFIIH Complex
Nucleus
Nucleoplasm
Holo TFIIH Complex
Molecular Function
Protein Binding
DNA Binding
Damaged DNA Binding
ATP-dependent DNA Helicase Activity
Protein Kinase Activity
Protein Binding
ATP Binding
GTP Binding
Protein C-terminus Binding
DNA-dependent ATPase Activity
Transcription Factor Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
ATPase Activity
DATP Binding
Peptide Binding
3'-5' DNA Helicase Activity
Protein N-terminus Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Nucleotide-excision Repair, DNA Duplex Unwinding
Nucleotide-excision Repair, DNA Damage Removal
Response To Hypoxia
DNA Topological Change
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Apoptotic Process
Response To Oxidative Stress
Protein Localization
Response To UV
UV Protection
Gene Expression
Viral Process
Nucleotide-excision Repair, DNA Incision
Hair Cell Differentiation
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Apoptotic Process
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
134 interactors:
ABT1
AKAP17A
ARHGEF3
ATP5O
ATXN7
BARD1
BEX2
BRMS1
BYSL
C11orf57
C1orf35
C7orf25
C8orf33
CARD9
CCDC85B
CCDC94
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
DAZAP2
DDX41
DDX6
DIEXF
DNAJB11
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM214B
FAM64A
GATAD2B
GCC1
GPATCH2L
GPATCH4
GPX7
HAUS1
HMGB4
HSPD1
IK
IQCE
KANK2
KANSL1
KAT7
KDM1A
KRT31
LAMTOR5
LENG1
LENG8
LIN37
MCM10
MEST
METTL17
MFAP1
MRPL44
NIPSNAP3A
NKAP
NOL12
NOP2
NRIP1
NUSAP1
PAM16
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PRKRIP1
PRPF31
PSMA1
RCOR3
RPL13
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TCEB3
TCEB3B
TEAD4
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC25
TTLL10
TXLNB
UTP11L
UTP14A
ZBTB16
ZBTB24
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZGPAT
ZNF136
ZNF148
ZNF169
ZNF227
ZNF239
ZNF266
ZNF302
ZNF329
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF439
ZNF490
ZNF555
ZNF572
ZNF578
ZNF587
ZSCAN12
26 interactors:
AR
BCR
CCNC
CCNH
CDK7
CDK8
CEP70
E2F1
ERCC2
GTF2E1
GTF2E2
GTF2H1
GTF2H2
GTF2H3
GTF2H4
GTF2H5
KPNA3
MNAT1
MSANTD2
PSMC5
RAD52
SRPK2
TP53
XIAP
XPC
ZSCAN1
Entrez ID
80321
2071
HPRD ID
16779
00593
Ensembl ID
ENSG00000114107
ENSG00000163161
Uniprot IDs
B7Z2D2
Q8NHQ1
G3V1S1
P19447
PDB IDs
4ERN
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
RRNA Processing
Regulation Of Cellular Process
RRNA Metabolic Process
Ribosomal Small Subunit Biogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
MRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone H3-K9 Dimethylation
RNA Processing
Chromatin Organization
Histone Modification
Maturation Of SSU-rRNA
Chromosome Organization
Cell Death
Death
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Apoptotic Process
Nucleotide-excision Repair, DNA Damage Removal
Transcription Initiation From RNA Polymerase II Promoter
Nucleotide-excision Repair
Transcription Elongation From RNA Polymerase I Promoter
DNA-templated Transcription, Elongation
Transcription From RNA Polymerase I Promoter
DNA-templated Transcription, Initiation
Transcription Elongation From RNA Polymerase II Promoter
Termination Of RNA Polymerase I Transcription
Transcription Initiation From RNA Polymerase I Promoter
7-methylguanosine MRNA Capping
7-methylguanosine RNA Capping
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Process
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Cellular Response To DNA Damage Stimulus
Viral Process
Regulation Of Viral Transcription
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA Catabolic Process
Regulation Of Viral Process
Transcription, DNA-templated
DNA Repair
RNA Biosynthetic Process
Regulation Of Cell Cycle
Cellular Response To Stress
RNA Metabolic Process
Positive Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
DNA Metabolic Process
Nitrogen Compound Metabolic Process
MRNA Processing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Aromatic Compound Catabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Metabolic Process
MRNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Processing
Regulation Of Gene Expression
Tagcloud
?
3b
aa8
adp
antiapoptotic
became
carrying
cho
concordance
confer
delay
determinant
ercc1
erk2
excision
g5
hamster
mtt
ner
ovary
pair
parental
phosphatidylinositol
pi
player
repair
ribose
uv24
withdrawal
xpb
Tagcloud (Difference)
?
3b
aa8
adp
antiapoptotic
became
carrying
cho
concordance
confer
delay
determinant
ercc1
erk2
excision
g5
hamster
mtt
ner
ovary
pair
parental
phosphatidylinositol
pi
player
repair
ribose
uv24
withdrawal
xpb
Tagcloud (Intersection)
?