NHERF4 and NOMO1

		NHERF4	NOMO1
Description		NHERF family PDZ scaffold protein 4	NODAL modulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Brush Border Membrane Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Multi-pass Translocon Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Protein Binding Carbohydrate Binding Ribosome Binding
	Biological Process	Monoatomic Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Protein Localization To Plasma Membrane	Determination Of Left/right Asymmetry In Lateral Mesoderm Multi-pass Transmembrane Protein Insertion Into ER Membrane Negative Regulation Of Nodal Signaling Pathway
Pathways		Intestinal infectious diseases
Drugs			Theophylline
Diseases
GWAS
Interacting Genes		18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	13 interacting genes: ATF7IP BAG6 DLG4 ECT2 EXOSC10 NCLN SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2
Entrez ID		79849	23420
HPRD ID		06191	11398
Ensembl ID		ENSG00000172367	ENSG00000103512
Uniprot IDs		B0YJ61 E9PPZ1 Q86UT5	Q15155
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?		Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity Transmembrane Transport Monoatomic Ion Transport Apical Plasma Membrane Sodium-independent Organic Anion Transport Sodium-independent Organic Anion Transmembrane Transporter Activity Transport Across Blood-brain Barrier Xenobiotic Transport Organic Anion Transport Monocarboxylic Acid Transport Carboxylic Acid Transport Organic Acid Transport Basal Plasma Membrane Quaternary Ammonium Group Transmembrane Transporter Activity Plasma Membrane Organic Hydroxy Compound Transport Organic Cation Transmembrane Transporter Activity Basolateral Plasma Membrane Quaternary Ammonium Group Transport Xenobiotic Export From Cell Vascular Process In Circulatory System Lipid Transport Tripeptide Transmembrane Transporter Activity Tripeptide Import Across Plasma Membrane Oligopeptide Transmembrane Transporter Activity Circulatory System Process Membrane Bile Acid And Bile Salt Transport Organic Cation Transport Amino-acid Betaine Transmembrane Transporter Activity Symporter Activity Dipeptide Transmembrane Transporter Activity Peptide:proton Symporter Activity Carnitine Transmembrane Transporter Activity Dipeptide Transport Dipeptide Import Across Plasma Membrane Dipeptide Transmembrane Transport Import Across Plasma Membrane Carnitine Transport Carnitine Transmembrane Transport Bile Acid Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Import Into Cell Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Amino-acid Betaine Transport Serotonin Transport PDZ Domain Binding Oligopeptide Transmembrane Transport Oligopeptide Transport
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