NHERF4 and SLC22A9

Number of citations of the paper that reports this interaction (PubMedID 15553237)
0

Data Source:
HPRD (two hybrid)

		NHERF4	SLC22A9
Description		NHERF family PDZ scaffold protein 4	solute carrier family 22 member 9
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Brush Border Membrane Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Organic Anion Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Short-chain Fatty Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Protein Localization To Plasma Membrane	Lipid Transport Hormone Transport Organic Anion Transport Short-chain Fatty Acid Transmembrane Transport Sodium-independent Organic Anion Transport Transmembrane Transport
Pathways		Intestinal infectious diseases
Drugs
Diseases
GWAS			Economic and political preferences ( 22566634) Sex hormone levels ( 26014426) Thyroxine levels ( 30824882)
Interacting Genes		18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	3 interacting genes: NHERF1 NHERF2 NHERF4
Entrez ID		79849	114571
HPRD ID		06191	06982
Ensembl ID		ENSG00000172367	ENSG00000149742
Uniprot IDs		B0YJ61 E9PPZ1 Q86UT5	Q8IVM8
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?		Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity Transmembrane Transport Monoatomic Ion Transport Apical Plasma Membrane Sodium-independent Organic Anion Transport Sodium-independent Organic Anion Transmembrane Transporter Activity Transport Across Blood-brain Barrier Xenobiotic Transport Organic Anion Transport Monocarboxylic Acid Transport Carboxylic Acid Transport Organic Acid Transport Basal Plasma Membrane Quaternary Ammonium Group Transmembrane Transporter Activity Plasma Membrane Organic Hydroxy Compound Transport Organic Cation Transmembrane Transporter Activity Basolateral Plasma Membrane Quaternary Ammonium Group Transport Xenobiotic Export From Cell Vascular Process In Circulatory System Lipid Transport Tripeptide Transmembrane Transporter Activity Tripeptide Import Across Plasma Membrane Oligopeptide Transmembrane Transporter Activity Circulatory System Process Membrane Bile Acid And Bile Salt Transport Organic Cation Transport Amino-acid Betaine Transmembrane Transporter Activity Symporter Activity Dipeptide Transmembrane Transporter Activity Peptide:proton Symporter Activity Carnitine Transmembrane Transporter Activity Dipeptide Transport Dipeptide Import Across Plasma Membrane Dipeptide Transmembrane Transport Import Across Plasma Membrane Carnitine Transport Carnitine Transmembrane Transport Bile Acid Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Import Into Cell Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Amino-acid Betaine Transport Serotonin Transport PDZ Domain Binding Oligopeptide Transmembrane Transport Oligopeptide Transport	Protein-membrane Adaptor Activity Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Protein Localization To Plasma Membrane Protein Localization To Cell Periphery Protein Localization To Membrane Apical Plasma Membrane Signaling Receptor Binding Phosphatase Binding Localization Within Membrane Apical Part Of Cell Beta-catenin Binding Renal Phosphate Ion Absorption Guanylate Cyclase Inhibitor Activity Molecular Adaptor Activity Regulation Of Renal Phosphate Excretion Dopamine Receptor Binding Endomembrane System Cellular Localization Intracellular Protein Localization Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Microvillus Assembly Channel Activator Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Beta-2 Adrenergic Receptor Binding Chloride Channel Regulator Activity Gamma-aminobutyric Acid Import Growth Factor Receptor Binding Negative Regulation Of CGMP-mediated Signaling Microvillus Organization Establishment Of Golgi Localization Phospholipase C-activating Dopamine Receptor Signaling Pathway Intracellular Phosphate Ion Homeostasis Glutathione Transport Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway Negative Regulation Of Sodium Ion Transport Gamma-aminobutyric Acid Transport Golgi Localization Maintenance Of Cell Polarity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Fibroblast Migration Cerebrospinal Fluid Circulation Regulation Of CGMP-mediated Signaling Ion Channel Inhibitor Activity Plasma Membrane Protein Complex Stereocilium Tip Oligopeptide Transport Establishment Of Epithelial Cell Apical/basal Polarity
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