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CDC73 and TFCP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CDC73
TFCP2
Gene Name
cell division cycle 73
transcription factor CP2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cdc73/Paf1 Complex
Cellular_component
Nucleus
Molecular Function
RNA Polymerase II Core Binding
Protein Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Sequence-specific DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Endodermal Cell Fate Commitment
Transcription, DNA-templated
MRNA Polyadenylation
Cell Cycle
Negative Regulation Of Cell Proliferation
Histone Monoubiquitination
Wnt Signaling Pathway
Stem Cell Maintenance
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of MRNA 3'-end Processing
Protein Destabilization
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Histone H2B Ubiquitination
Negative Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Cellular Response To Lipopolysaccharide
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
Hedgehog 'on' state
formation of the beta-catenin:TCF transactivating complex
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by Hedgehog
Signaling by Wnt
Signaling by WNT in cancer
Drugs
Diseases
GWAS
Subcutaneous adipose tissue (
22589738
)
Protein-Protein Interactions
30 interactors:
ALAS1
ANXA6
CCDC155
CEP70
CTNNB1
DDAH2
FAF1
FSD2
GC
GOLGA2
HAP1
HIST1H1C
HSF2BP
HSPA4
ITFG1
KCNH2
KIAA1549
KIDINS220
MCM3AP
MTUS2
PITHD1
RNF20
RNF40
TCEA1
TCF4
TFCP2
TOMM20
TSGA10
VPS37B
WWC1
62 interactors:
ADPRH
APBB1
ASAP3
BAG6
C19orf73
CA1
CASP8
CBX8
CCDC94
CDC73
COIL
DNAJC27
DNAJC5B
DPH1
E2F8
EAF1
EIF5B
EPHA10
FAM64A
FANCL
FARS2
FBXL18
GPANK1
HDAC1
HDAC2
IRAK1BP1
KIAA1598
MAPK1
MAPK14
MAPK8
MOB3C
MORF4L1
MRPL11
MRPL40
MVP
NABP1
NFE4
NOM1
NPEPL1
PHF1
PITPNM1
PLCB1
POLL
POLR3GL
PPIG
PPP1R1B
PPP3R2
PSMD5
RBMS1
RNF2
SDCBP
SIN3A
STMN2
SUMO1
TCEA2
TDRD1
TRAPPC12
TSPAN12
UBP1
YY1
ZCCHC10
ZCCHC12
Entrez ID
79577
7024
HPRD ID
09581
01790
Ensembl ID
ENSG00000134371
ENSG00000135457
Uniprot IDs
Q6P1J9
Q12800
PDB IDs
Enriched GO Terms of Interacting Partners
?
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2B Ubiquitination
Cellular Localization
Positive Regulation Of Glycoprotein Biosynthetic Process
Establishment Of Localization In Cell
Genitalia Morphogenesis
Positive Regulation Of Glycoprotein Metabolic Process
Organelle Organization
Histone Monoubiquitination
Regulation Of Glycoprotein Biosynthetic Process
Establishment Of Protein Localization To Organelle
Protein Localization
Chromosome Organization
Histone Ubiquitination
Protein Import
Positive Regulation Of Epithelial To Mesenchymal Transition
Cellular Process
Cytoplasmic Transport
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Histone Methylation
Intracellular Transport
Positive Regulation Of Neurogenesis
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Organ Growth
Organelle Localization
Transcription-coupled Nucleotide-excision Repair
Regulation Of Oligodendrocyte Differentiation
Protein Targeting
Protein Monoubiquitination
Myoblast Differentiation
Regulation Of Intracellular Transport
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Chromosome Localization To Nuclear Envelope Involved In Synapsis
Negative Regulation Of Potassium Ion Export
Regulation Of Myelination
Positive Regulation Of Intracellular Signal Transduction
Skin Morphogenesis
Vesicle Localization
Regulation Of Histone Methylation
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Development
Genitalia Development
Regulation Of Intracellular Signal Transduction
Skin Development
Regulation Of Epithelial To Mesenchymal Transition
Protein Localization To Organelle
Protein Transmembrane Transport
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Response To DNA Damage Stimulus
Cellular Metabolic Process
Cellular Response To Stress
Chromatin Modification
Cellular Protein Metabolic Process
Histone Modification
Chromatin Organization
Negative Regulation Of Gene Expression
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Protein Metabolic Process
Histone Deacetylation
Regulation Of Gene Expression
Chromosome Organization
Regulation Of Metabolic Process
Protein Deacetylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Activation Of Innate Immune Response
Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Stimulus
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Regulation Of Organelle Organization
Negative Regulation Of Gene Expression, Epigenetic
Cellular Protein Modification Process
Negative Regulation Of RNA Biosynthetic Process
Peptidyl-amino Acid Modification
Toll-like Receptor 4 Signaling Pathway
Anatomical Structure Development
Anatomical Structure Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Tagcloud
?
1379delt
affecting
caucasian
encoded
fibroma
hpt
hyperparathyroidism
hystologically
instrumental
jaw
jt
l460lfs
mandible
modelling
moiety
mtt
ossifying
parafibromin
parathyroid
partners
proband
pth
relatives
sanger
sca
silico
terminus
underlie
vast
Tagcloud (Difference)
?
1379delt
affecting
caucasian
encoded
fibroma
hpt
hyperparathyroidism
hystologically
instrumental
jaw
jt
l460lfs
mandible
modelling
moiety
mtt
ossifying
parafibromin
parathyroid
partners
proband
pth
relatives
sanger
sca
silico
terminus
underlie
vast
Tagcloud (Intersection)
?